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January and Brandon talk about sex! January talks about the importance of communication and explains all the things a new mom struggles with that prevents sex from happening and Brandon gives the male point of view on how to cope with the agonizing sexual drought. Also, Brandon tries to figure out Januarys favorite position but shes too pissed about the lone baby sock no one is picking up in the corner of the hall!
How to Do You, Boo with January Harshe has opened up registration for Dallas, Detroit, and Minneapolis on BWFConference.com. If you struggle with body image, self love, self care, too little time, or too little money, you are not alone. Join January for an afternoon of information, instruction, and inspiration that has taken her many years to learn, implement, and successfully apply to her own life.
To receive a $100 discount code on one of these special events, simply DM January...
The science has been obscured in philosophy, but the question is settled. The question of when a human life begins is a strictly scientific one and one for which the scientific community has had an empirical, internationally acknowledged answer for a very long time. For more than a century, the field of human embryology has documented that in human sexual reproduction a new, whole, individual, living human being begins to exist at "first contact" between a sperm and an oocyte/"egg" (the beginning of the process known as fertilization.) Immediately when these two mere cells make first contact and fuse, organism proteins and enzymes specific to humans are produced. One new single-cell human being with his or her own new, unique, and complete set of human DNA begins to exist. This is an internationally recognized empirical fact that has been documented by the Carnegie Stages of Early Human Embryonic Development since 1942, and updated every year since then to the present by the international nomenclature committee (FIPAT). The 23 Carnegie Stages cover human development during the eight-week embryonic period, and a new human being is represented by Carnegie Stage 1a.
Anna Hunt, Staff Writer
A team of Danish and French researchers have found that ibuprofen may be one of the culprits responsible for male infertility. The study showed that daily intake of the drug creates a hormonal condition associated with impaired fertility, depression and increased risk of cardiovascular events.
Ibuprofen is one of the most common over-the-counter pain relief medicines. The medical industry categorizes it as a non-steroidal anti-inflammatory drug (NSAIDs). Because the drug is readily available without a prescription, most people think its safe. As well, with OTC drugs there is typically no medical professional to raise attention to the potential side-effects of the drug.
Scientific research has already implicated ibuprofen as having some negative effects on our health. Now, this new clinical study has found that ibuprofen may be one of the causes of male infertility. The research team writes:
Using a unique combination of a randomized, controlled clinical trial and ex vivo and in vitro approaches, we report a univocal depression of important aspects of testicular function, including testosterone production, after use of over-the-counter ibuprofen.
The study shows that ibuprofen use results in selective transcriptional repression of endocrine cells in the human testis. This repression results in the elevation of the stimulatory pituitary hormones, resulting in a state of compensated hypogonadism, a disorder associated with adverse reproductive and physical health disorders.
Bernard Jgou, director of the Institute of Research in Environmental and Occupational Health in France, was one of the authors of the study. In an interview with CNN, he explained the research process:...
The Skeptical Raptor, stalking pseudoscience in the internet jungle.
Although I have no poll numbers sitting in front of me, and certainly no scientific peer-reviewed research, I just have a feeling that if you scratch the surface of an anti-vaccine activist, you will find that if they could hate one vaccine, it would be Gardasil. And one of the arguments will be all about
Charges against five men accused of being in a pedophile ring have been dropped two weeks before trial and their accuser labelled "serial fantasist" after it was revealed the woman had made false allegations on multiple occasions. A medical expert also said that the woman's account of her backyard abortion - allegedly performed on her by one of the accused - had been lifted from TV show portrayals of abortions on programs like 'Call the Midwife' and the film 'Vera Drake'. In 2016 the woman, who cannot be identified for legal reasons, made accusations against the men, saying that she had been abused at parties between 3 and 15 years of age. She said she was forced to have an abortion and help the men torture other kids. The allegations saw retired GP Stephen Glascoe, 67, retired social worker Patrick Graham, 61, and three other men due to stand trial on January 29 for their alleged involvement in a Cardiff pedophile ring in the 1990s. During her most recent rape accusations, the woman told police that one of the men had sent her a package from Amazon that included wires twisted in the very same way that her hands had been allegedly tied while they abused her. She later conceded that she had actually ordered the parcel herself.
The Womens March is preparing to mark the one year anniversary of its march in Washington D.C. in Las Vegas on January 21st, but theres something important missing from the groups list of eight Unity Principles. This year, the organization is focused on registering voters to obtain tangible strategies and concrete wins in 2018.
The march has provided a platform for a national discussion of womens issues, and to guide this conversation, the march organizers wrote a series of eight Unity Principals that are intended to be the cross section of intersectional feminism. Two of the principals that have been particularly relevant this year those on ending violence and on reproductive rights.
As we saw in the second half of 2017, it unfortunately still needs to be said that women stand against all forms of violence against our bodies. Sexual assault is something we must identify and condemn as a culture, and specifically as women. Reproductive rights also continue to dominate the conversation, although the movement has run into some trouble over the issue of abortion, since pro-life feminists have added their voice to the conversation around the march.
But the conversation around reproductive rights is missing an important issue. There is a large group of women whose problems have been omitted. These are the women and families who have suffered pregnancy loss (and its ugly sisters; stillbirth and infertility, which are deserving of their own time and will not be addressed here).
If we are going to talk about womens issues, and specifically reproduction, it seems negligent not to include pregnancy loss. The statistics regarding pregnancy loss are staggering with as many as 1 in 4 pregnancies ending in miscarriage. Pregnancy loss hurts women and it does not discriminate. It does not matter if you are pro-choice or pro-life, Catholic or Buddhist, Republican or Democrat, rich or poor. It doesnt matter if you wanted the baby for years or if you were planning on having an abortion. Women across all demographics have experienced pregnancy loss, yet it is a largely ignored issue, even among women.
One might argue that the Womens March does not need to focus on pregnancy loss because everyone agrees that it is bad, and because its not an injustice caused by society. But treating it as simply a naturally occurring tragedy is an injustice.
In a conversation largely dominated by reproductive choice, we have forgotten those who know all too well that sometimes pregnancy and...
Certified Birth & Bereavement Doula serving southeastern Wisconsin
This time is by launching her Family Planning Programme. The technology is called Uniiject, it comes in a simple, unintimidating squeeze bottle. It is said to cost one dollar.
The injection is simple and built to encourage more women in West African nations to either delay pregnancy or halt it forever . Because the injection doesnt require the women to lift up their dresses, turnout is expected to be high.
According to Science Alert, 6,000 women have already been subjected to the anti-fertility injections.
The results have so far been very positive in Burkina Faso, with Gates Foundation-funded site, Take Part, reporting that nearly 6,000 women have used the contraceptive, and for almost a quarter of them, its the first contraceptive theyve ever taken.
Melinda Gates now plans to roll out the anti-fertility contraception to millions of women, according to the Hindustan Times.
Im encouraged that the government of India is finally, really coming back to family planning. They have re-energised it, they are saying they understand it needs to be voluntary and they are starting to offer a basket of choices and options to women, said Melinda , co-chair of the Bill and Melinda Gates Foundation, who arrived in New Delhi on a three-day visit on Friday.
Because sterilisation is the only method available to so many women, they have their children very, very close together, so they have them young which is extremely dangerous for the mom and for the baby, she said.
So India took this decision last year to introduce injectables into the public sector, which is huge. I see it happening this year. They (Indian government) have been talking about it for several years but hadnt taken the policy decision. They finally took the policy decision, so I think...
President Trump will be the first sitting U.S. president to directly address the March for Life anti-abortion rally in Washington.
The Skeptical Raptor, stalking pseudoscience in the internet jungle.
According to recent studies from the CDC, only about 63% of teen girls and 50% of teen boys have started the HPV vaccination series. The relatively low vaccine uptake, despite the evidence that Gardasil prevents cancer, one of the few ways to actually prevent cancer, is especially frustrating to those of us who are supporters
PMID: Cell Physiol Biochem. 2017 ;44(6):2407-2421. Epub 2017 Dec 18. PMID: 29268276 Abstract Title: Melatonin Relieves Busulfan-Induced Spermatogonial Stem Cell Apoptosis of Mouse Testis by Inhibiting Endoplasmic Reticulum Stress. Abstract: BACKGROUND/AIMS: Busulfan is commonly used for cancer chemotherapy. Although it has the advantage of increasing the survival rate of patients, it can cause male infertility via damaging the testes and reducing sperm counts. Therefore, the underlying mechanism should be explored, and new agents should be developed to protect the male reproductive system from busulfan-induced damage. Endoplasmic reticulum stress (ERS) is considered a key contributor to numerous pathologies. Despite several studies linking ERS to toxicants, studies have yet to determine whether ERS is a contributing factor to busulfan-induced testicular damage. Melatonin is a well-known broad-spectrum antioxidant, anti-inflammatory and antitumour agent, but the effects of melatonin on busulfan-induced ERS in mouse testes damage are less documented.METHODS: The effects of melatonin were measured by immunofluorescence staining, Western blot, qRT-PCR analysis and flow cytometry assay. The underlying mechanism was investigated by measuring ERS.RESULTS: We found that ERS was strongly activated in mouse testes (in vivo) and the C18-4 cell line (in vitro) after busulfan administration. ERS-related apoptosis proteins such as caspase-12, CHOP and caspase-3 were activated, and the expression of apoptotic proteins such as P53 and PUMA were upregulated. Furthermore, we investigated whether melatonin reduced the extent of damage to mouse testes and improved the survival rates of busulfan-treated mice. When exploring the underlying mechanisms, we found melatonin could counteract ERS by decreasing the expression levels of the ERS markers GRP78, ATF6, pIRE1 and XBP1 in mouse testes and mouse SSCs (C18-4 cells). Moreover, it blocked the activation of ERS-related apoptosis proteins caspase-12, CHOP and caspase-3 and suppressed P53 and PUMA expression stimulated by busulfan both in vivo and in vitro.CONCLUSION: Our results demonstrate that ERS is an important mediator for busulfan-induced apoptosis. The attenuation of ERS by melatonin can prevent busulfan-treated SSCs apoptosis and protect busulfan-treated testes from damage. Thus, this study suggests that melatonin may alleviate the side effects of busulfan for male patients during clinical treatment.
It was reported this week a simple kitchen staple could help to reduce the number of c-sections. According to the new study published in the Journal of Maternal-Fetal & NeoNatal Medicine, bicarbonate of soda could help to reduce the number of women having c-sections because of failure to progress. Failure to progress is one of the leading reasons why women give birth by c-section. Failure to progress is described as a slow or stalled labour. It is usually used to describe a first labour of over 20 hours or a labour of over 14 hours for a woman who has given birth previously. You can read more in Failure To Progress - 6 Things That Prolong Labour.
PMID: Toxicol Appl Pharmacol. 2017 Dec 28 ;340:30-38. Epub 2017 Dec 28. PMID: 29289671 Abstract Title: Melatonin protects mouse spermatogonial stem cells against hexavalent chromium-induced apoptosis and epigenetic histone modification. Abstract: Given the potential biological functions of spermatogonial stem cells (SSCs) in spermatogenesis and in delivering parental genetic information to the next generation, how these cells respond to environmental toxins and carcinogens should be investigated. We examined the toxic effect of hexavalent chromium (Cr(VI)) on global histone modifications and apoptotic signaling pathways in SSCs. We determined the effect of melatonin, one of the most powerful endogenous free radical scavengers and wide-spectrum antioxidants, in protecting SSCs from Cr(VI)-induced apoptosis and global histone modification by Western blot analysis. In addition, we examined the in vivo effect of melatonin on Cr(VI)-induced histological changes of seminiferous tubules in mouse testes. We also evaluated the fertility of male mice by monitoring litter size following intraperitoneal injection of these chemicals. Our study demonstrated the Cr(VI)-induced global increases in H3K9me3 and H3K27me3 and activated the apoptotic signaling pathway. Pretreatment of SSCs with melatonin alleviated Cr(VI)-induced apoptosis and the global increase of H3K9me3. Exposure to melatonin also attenuated the Cr(VI)-induced increase of the abundance of histone methyltransferase ESET. Furthermore, exogenous administration of melatonin protected mice against Cr(VI)-induced changes in testicular histology and germ cell apoptosis, which helped maintain normal spermatogenesis and male fertility. Our study revealed a potential new therapeutic approach for male reproductive injury caused by Cr(VI).
PMID: Cell J. 2018 Apr ;20(1):108-112. Epub 2017 Dec 1. PMID: 29308626 Abstract Title: Evaluating The Effect of Melatonin on HAS2, and PGR expression, as well as Cumulus Expansion, and Fertility Potential in Mice. Abstract: OBJECTIVES: Infertility is a worldwide health problem which affects approximately 15% of sexually active couples. One of the factors influencing the fertility is melatonin. Also, protection of oocytes and embryos from oxidative stress inducing chemicals in the culture medium is important. The aim of the present study was to investigate if melatonin could regulate hyaluronan synthase-2 (HAS2) and Progesterone receptor (PGR) expressions in the cumulus cells of mice oocytes and provide an in vitro fertilization (IVF) approach.MATERIALS AND METHODS: In this experimental study, for this purpose, 30 adult female mice and 15 adult male mice were used. The female mice were superovulated using 10 U of pregnant mare serum gonadotropin (PMSG) and 24 hours later, 10 U of human chorionic gonadotropin (hCG) were injected. Next, cumulus oocyte complexes (COCs) were collected from the oviducts of the female mice by using a matrix-flushing method. The cumulus cells were cultured with melatonin 10M for 6 hours and for real-time reverse transcription-polymerase chain reaction (RT-PCR) was used for evaluation of HAS2 and PGR expression levels. The fertilization rate was evaluated through IVF. All the data were analyzed using a t test.RESULTS: The results of this study showed that HAS2 and PGR expressions in the cumulus cells of the mice receiving melatonin increased in comparison to the control groups. Also, IVF results revealed an enhancement in fertilization rate in the experimental groups compared to the control groups.CONCLUSIONS: To improve the oocyte quality and provide new approaches for infertility treatment, administration of melatonin as an antioxidant, showed promising results. Thus, it is concluded that fertility outcomes can be improved by melatonin it enhances PGR.
Pope Francis has awarded a family planning clinic millions of dollars of Vatican money, in his first public endorsement for abortion. On January 12, reports surfaced on Twitter that Lilianne Ploumen, former Minister for Foreign Trade [...]
A new Marist poll reveals more than three quarters of Americans would restrict abortion to, at most, the first trimester of pregnancy. The poll, sponsored by the Knights of Columbus, is released as thousands begin to descend upon Washington, DC for the annual March for Life. The survey finds that 76 percent of Americans are in favor of limiting abortion to, at most, the first three months of pregnancy, including 92 percent of Republicans, 78 percent of Independents, and 61 percent of Democrats. Additionally, while 51 percent of Americans identify as "pro-choice," even 60 percent of those agree with substantial restrictions on abortion.
Originally published in 2012; link to Amazon Smile that donates a portion of proceeds to ICAN
For those who dont know where it all began, Ill start with my first pregnancy. August 2008 I got pregnant with my DD and worked with the Midwife Center to attempt a natural delivery. The entire pregnancy was full of complications, which I wont go into, but it came down to me going 41 weeks when they eventually diagnosed me as having preeclampsia and offered a c-section or induced labor. No labor signs had come up to that point so I elected the routine section given my daughter didnt seem ready to come out anyway. Recovery was very hard, but I got by.
Three months postpartum, I discovered that I was pregnant again and, needless to say, shocked, but learned about VBACs and found a practice that supported my desire to attempt one. This pregnancy went fine except for the fact that it was full of stress having to move, take care of my DD, and mentally and physically prepare to have another child within a year. I tried everything to go into labor naturally using the advice of a wonderful doula I was working with but wound up going 42 weeks and a day without any signs of labor. After getting an ultrasound, they found that my amniotic fluids were dropping and urged that I get my son out asap. With much remorse, I consented to have a repeat section given I really had no choice; obviously, I wanted my son to come out alive. While they were performing the operation, they discovered that the lining of my uterus was so thin they could see my son through it (aka dehiscence) and said it was good that I didnt labor since I would have ruptured. The recovery was very rough and throughout the following year, I had numerous health issues which I attribute to having two surgeries so close together.
Fast forward to August 2011. I got pregnant again. Returned to my former OB/GYN practice only to be told that they were not very supportive of me attempting a VBA2C. I went looking at other practices only to be told repeatedly that they would not allow me to VBA2C since it was too dangerous and I could rupture. Desperate, I contacted the Doulas of Pittsburgh in January seeking advi...
A proposed rule under review at the White House would create a new division of conscience and religious freedom division inside the Health and Human Services Department (HHS) that would allow healthcare providers to opt out of treating patients or offering services that go against their moral and religious beliefs such as performing abortions or
A proposed rule under review at the White House would create a new division of conscience and religious freedom division inside the Health and Human Services Department (HHS) that would allow healthcare providers to opt out of treating patients or offering services that go against their moral and religious beliefs such as performing abortions or working with LGBT patients.
Before each high school dance, my husband and I must participate in an unnerving and relatively new phenomenon: The pre-dance picture party. One brave family (usually us) offers to host my daughters large circle of friends and their parents for an extended photo shoot to capture the big night. Both moms and dads even siblings are expected to attend, dedicating a chunk of their Saturday night to participate in the festivities.
Weve had upwards of 50 people in our house, served food and drinks, and watched parents wielding high-powered digital cameras take loads of pictures before the teens head out. Its like a red-carpet event where our daughters are the celebrities. The moms promptly post a collage on Facebook, adding to a lengthy thread of photographed moments that catalog their childs life. The photos are then loaded onto computers for safekeeping.
The picture party circus is unlike anything my parents would have tolerated, let alone participated in, and its just one example of how technology has fueled the child-centered world that we, as parents, have created. Its hard to imagine such a scrum would exist but for social media and weaponized cameras. While we lament how much our teens are addicted to technology giving rise to an alarming epidemic of narcissism, insularity, and indifference among our nations youth we have yet to really look at how our own use of technology has fostered this.
Thats one angle in a new episode of Netflixs Black Mirror, which gives a glimpse into where the trajectory of emerging technology and parenting could potentially collide. In Arkangel, directed by Jodie Foster, a single mother raising her only child in a working-class neighborhood has an implant inserted into the brain of her three-year-old daughter after she goes missing from a local park for a brief time.
The implant allows the mother, Marie, to track the whereabouts of her daughter, Sarah, on a computerized tablet. Apps on the tablet enable Marie to blur out violent images that Sarah might see on television and prevent the girl from seeing real-life threats like an aggressive dog, schoolyard bully or even her ill grandfather. Marie can watch everything thats happening to Sarah in real-time, even monitor her physical health. Every moment is saved on the tablet, and Marie dutifully checks the device throughout the day to make sure Sarah is safe.
When the girl reaches grade school, shes mocked by classmates for her robotic personality. Out of curiosity, Sarah starts to ask them questions. After a boy asks her if shes ever seen blood before (she hasnt), then tries to describe it to her, Sarah goes home and stabs herself with a pencil to draw blood. Marie, alarmed at what shes done to her daughter, packs away the tablet.
Several years later, when Marie discovers teenage-Sarah lied...
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