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Saturday, 23 September

03:07

NIH-Supported Journal Publishes Landmark Study Linking Fluoride to Low IQ Natural Blaze

By Jay Syrmopoulos

Increased levels of prenatal fluoride exposure have been linked to lower intelligence in children, according to the results of a new study.

In the eye-opening new peer-reviewed study, published on September 19, 2017, in the journal Environmental Health Perspectives, researchers found strong evidence of a link between fluoride and lower cognitive function in children.

With an impact factor of 9.78, Environmental Health Perspectives is one of the most highly ranked journals in Toxicology, Public, Environmental and Occupational Health, and Environmental Sciences.

The researchers found that higher levels of maternal urinary fluoride during pregnancy (a proxy for prenatal fluoride exposure) that are in the range of levels of exposure in other general population samples of pregnant women as well as nonpregnant adults were associated with lower scores on tests of cognitive function in the offspring at 4 and 612 y old, according to the study.

The study involved 1,576 samples taken from over 300 sets of mothers and children in Mexico by a research team from Toronto. The researchers tested the childrens cognitive development twice over the course of 12 years. In Mexico, fluoride is not added to the public water supply, but people are exposed through naturally occurring fluoride in water, toothpaste, fluoridated salt and other supplemental products.

Childhood exposure to fluoride is safer than prenatal. There is pretty good science now to support the fact that the fetal system tends to be more sensitive to environmental toxicants than once the child is born, said the studys lead author, Howard Hu, founding dean of the Dalla Lana School of Public Health at the University of Toronto, according to CNN.

The authors of the study looke...

02:42

Aluminum Adjuvants and Autism The Driven Researcher

New Animal Study Confirms Male Susceptibility to Injury from Neurotoxin

For decades, regulatory agencies in the United States have given a free pass to aluminum adjuvants in vaccines. Vaccine manufacturers include the adjuvants in many of their products to generate a stronger immune response. A new study in the Journal of Inorganic Biochemistry from Christopher Shaws lab at the University of British Columbia (UBC) adds to the mounting body of evidence indicating that this free pass is undeserved. The study uses a mouse model to show that, far from being safe, aluminum adjuvants are neurotoxic agents capable of sabotaging normal development and contributing to autism, especially in males.

02:41

New Study Confirms Fluoride Harms Fetal Brain; Lowers IQ Fluoride Action Network

The results of the first ever U.S. government funded study of fluoride and IQ have just been published. A team of researchers found a statistically significant association between fluoride exposure in women during pregnancy and a lowering of IQ in their children, reports the Fluoride Action Network.

The study was published in Environmental Health Perspectives by scientists from the University of Toronto, University of Michigan, Harvard, McGill, and the national public health agency of Mexico. It was funded by the National Institute of Environmental Health Sciences, with over $3 million in grants.

The study was conducted in Mexico City using a long-running cohort of women-infant pairs that have been studied extensively for effects of environmental neurotoxins such as lead and mercury. It found an average loss of 5 to 6 IQ points among children of mothers with urine fluoride levels of 1.5 mg/L compared to those with 0.5 mg/L. For an entire population, such a loss would be expected to halve the number of geniuses in society and double the number of mentally handicapped. For IQ measured at 4 years of age, there was no apparent fluoride exposure threshold below which the effect leveled out.

The mothers in this study had a range of fluoride exposures similar to that found in fluoridating countries like the United States.

According to the lead investigator and professor of environmental health, epidemiology and global health at the University of Toronto, Dr. Howard Hu,

the study also suggests that the pre-natal nervous system may be more sensitive to fluoride compared to that of school-aged children.

Experts in the field of environmental toxicology have said the results are a huge red flag:

This is a very well-conducted study, and it raises serious concerns about fluoride supplementation in water. These new insights raise concerns that the prenatal period may be highly vulnerable and may require additional reconsideration, says Dr. Leonardo Trasande, a pediatrician who studies potential links between environmental exposures and health problems at New York University Langone Health. (Newsweek, 9/19/17)

Chris Neurath, research director for FAN agrees,

The loss of IQ is very large, as large as in previous studies from China where fluoride exposure levels were typically higher. The study was meticulously done and controlled for a wide range of potential spurious factors such as lead, mercury, socio-economic status, smok...

02:01

Dairy Free Fermentation: How to Ferment Without Whey The Healthy Home Economist

dairy free fermentationIn my latest eBook Real Food Fermentation Favorites (available here for a limited time until Monday, September 25 at midnight!), I discuss the history and enormous benefits of consuming fermented foods and beverages on a regular basis. Many recipes are provided with guidance on which ones are best for particular health challenges.

You may have noticed that many traditional fermentation recipes recommend raw whey as the probiotic starter culture. This provides the beneficial bacterial medium necessary to kick start the fermentation process. Within a few days, this synergistic mix creates a plethora of additional enzymes and boosted vitamin content. Simple raw foods transform into super raw foods.

The problem is that milk is the source of liquid whey. What about folks who have a dairy allergy? Is there another approach to fermenting foods and beverages that avoids whey as the microbial inoculant? (...)
Read the rest of Dairy Free Fermentation: How to Ferment Without Whey (604 words)

The post Dairy Free Fermentation: How to Ferment Without Whey appeared first on The Healthy Home Economist.

01:49

Survival Medicine Hour: Earthquake, Birthing Supplies, Hemorrhage, More Doom and Bloom (TM)

Survival Medicine Hour #355 What would you have done if you were in Mexico City during the recent earthquakes? Is there anything that might have increased your chances of survival? In this episode of the Survival Medicine Hour, hosts Joe Alton MD and Amy Alton ARNP talk about earhtquakes in general and give you safety tips that could save a life. Plus, what supplies would you need for delivering a baby and caring for a pregnancy in tough times? Nurse

[... Continue Reading]

01:49

Lactobacillus plantarum BS22 promotes gut microbial homeostasis in broiler chickens exposed to aflatoxin B1. GreenMedInfo

PMID:  J Anim Physiol Anim Nutr (Berl). 2017 Aug 3. Epub 2017 Aug 3. PMID: 28771826 Abstract Title:  Lactobacillus plantarum BS22 promotes gut microbial homeostasis in broiler chickens exposed to aflatoxin B1. Abstract:  Probiotics promote the health of the host by maintaining intestinal microbial homeostasis. This study aimed to investigate the benefits of Lactobacillus plantarum BS22 (LP) in the gastrointestinal tract (GIT) microbial homeostasis of broiler chickens exposed to aflatoxin B1 using the PCR-DGGE, viable count and real-time PCR. The toxin adsorption experiment demonstrated that treatment R5 (1.0  10(8) CFU/g LP) exhibited good absorptive effect in adsorbing the aflatoxin B1 (AFB1 ) in vitro. DGGE showed that the composition and structure of gut microbiota were more similar in the mucosa than in the content of all the samples. In addition, higher diversity of the microbiota was observedin the caecum and glandular stomach than in other segments. Lactobacillus, Enterococcus and Enterobacteriaceae were more abundant in the ileum than in the other segments. Enterobacteriaceae in groups I (basal diet) and II (basal diet+50 g/kg AFB1 ) showed a significant difference in group III (basal diet + 50 g/kg AFB1  + 1  10(8) CFU/g LP) in the crop content and duodenum mucosa (p 

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01:02

Prominent food researcher retracts paper from JAMA journal, replaces it with multiple fixes Retraction Watch

Earlier this week, we reported that high-profile food researcher Brian Wansink whos faced months of criticisms about his research had issued his second retraction. On Thursday, he issued his third. The retracted paper a 2012 research letter in the Archives of Pediatrics and Adolescent Medicine, now JAMA Pediatrics reported that children []

The post Prominent food researcher retracts paper from JAMA journal, replaces it with multiple fixes appeared first on Retraction Watch.

00:41

Magic Mushrooms Could Be a Life Saving Insect Repellent Natural Blaze

magic mushrooms insect repellent

By Aaron KeselNatural Blaze

A team of scientists headed by Jason Slot at Ohio State University compared genomes of three different hallucinogenic mushrooms with three non-hallucinogenic relatives. The experiment identified the cluster of genes responsible for making psilocybin, New Scientist reported.

Hallucinogenic mushrooms are often found in areas rich in fungi-eating insects, so Slot suggests the chemical in magic mushrooms psilocybin might protect the fungi by repelling insects, potentially influencing their behavior in some way.

The specific purpose of many secondary metabolites is unknown, says...

00:20

Will Opioid Lawsuits By County Officials Against Big Pharma Set Legal Precedent To Sue Vaccine Makers? Natural Blaze

By Catherine J. Frompovich

They know what theyve been doing. Theyve been misrepresenting the dangers of these dangerous addictive drugs for years. State Rep. Gen DiGirolamo

Those pharmaceutical companies have made billions of dollars off the deaths of our children and our loved one. Delaware County Councilman David White

Big Pharma companies have a significant presence in the suburban counties surrounding Philadelphia, Pennsylvania.  However, being neighbors doesnt matter, since Delaware County, the SE Pennsylvania county constituting some of Philadelphias western suburbs, filed a lawsuit on September 21, 2017 against eleven pharmaceutical companies regarding the overwhelming opioid epidemic and problem.

The reason for the lawsuit is the amount of money Delaware County had, and has, to pay for all types of services rendered and other expenses due to opioid drug abuses.

Delaware County, represented by Attorney Robert J. Mongeluzzi of Saltz Mongeluzzi & Barrett, a Philadelphia law firm, filed a civil suit against pharmaceutical companies and the medical doctors who advised the companies regarding misinformation provided by the drug makers to physicians and others.

Attorney Mongeluzzi said the lawsuit will show Big Pharma funded false companies which Created disinformation to hoodwink and convince doctors that opioids werent addictive.  Rumblings of tobacco science there?

...

00:09

The Japanese Just Found a Sweet Solution to Sleep Loss Natural Blaze

sleep loss stress

By Heather CallaghanEditor

There are plenty of prescriptions and over-the-counter drugs for insomnia. But rarely do they target sleep deprivation caused by acute stress. And the world has plenty to be stressed about current events, wage reduction and job loss are major stress events.

Stress insomnia is one of the most tortuous, vicious cycles anyone can be in. You can lose sleep due to stress, and the sleep loss can cause you to be further stressed they cycle begins again. Furthermore, sleep loss can be due to health problems like obesity, diabetes, and cardiovascular diseases, which heap their own stressors on a fatigued person. The lack of restorative rest contributes to these problems.

Scientists from the Japanese Sleep Institute made an interesting new discovery about an already existing compound and it comes from sugar cane!

The compound is called octacosanol and its actually readily available from common plants such as rice bran, wheat germ, eucalyptus, other...

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Friday, 22 September

22:30

Reader complaints prompt retraction of meta-analysis of heart-failure drug Retraction Watch

A cardiology journal has retracted a 2016 meta-analysis after the editors had an, ahem, change of heart about the rigor of the study. The article, Ivabradine as adjuvant treatment for chronic heart failure, was published in the International Journal of Cardiology, an Elsevier title. The authors, a group at the Federal University of So Paulo, []

The post Reader complaints prompt retraction of meta-analysis of heart-failure drug appeared first on Retraction Watch.

22:30

Maximized Living: 5 Essentials of Chiropractic Marketing Propaganda Science-Based Medicine

What do vitalism, old school chiropractic subluxations, germ theory denial, detox supplements, marketing gimmicks, and practicing way beyond a reasonable scope have in common?

20:33

What is Brain Fog: The Mental Fatigue That Ruins Your Mood Mad In America

From ZME Science: More people than ever before are regularly experiencing brain fog, a collection of symptoms including fatigue, inability to focus, memory deficiency, confusion, and lack of mental clarity, due to our fast-paced industrialized lifestyles. A number of relatively simple lifestyle changes can help reduce brain fog, such as getting more sleep, minimizing stress, and eating a more balanced diet.

Article

20:33

Thou Shall Not Criticize Our Drugs Mad In America

One of the hallmarks of institutional corruption is that an institution will regularly act in ways that promote its own interests, even if that means betraying the principles that are supposed to govern that institution. In the world of medical journals, the public assumes that the journal will seek to publish research articles that report on the safety and efficacy of treatments, regardless of whether the findings support common beliefs and practices. In addition, the public assumes that a journal will publish letters-to-the-editor that, when written by knowledgeable people in the field, raise questions about a recent article the journal has published.

Such are the dictates of science. A medical journal is expected to promote an open-minded discussion of treatments, even if findingsor criticismsthreaten conventional beliefs.

In a blog published on September 21, Peter Gtzsche detailed a letter that he and I had submitted to World Psychiatry, related to an article on the 10-year outcomes of 281 Norwegian patients following a first episode of psychosis. The death rate in that study was quite high (11%), and we thought the authors should have reported in some detail on those deaths in their published article.

I wasnt surprised by this rejection of our letter. As a non-academic, I really dont have standing to write a letter to the editor of a medical journal, and although Peter Gtzsche certainly has such standing, I thought there was little chance our letter would be published. There is a long history of editors of psychiatry journals rejecting articles that challenge the merits of psychiatric drugs in a fundamental way, or only accepting such articles if the damaging results are downplayed or presented in an obscure way. In psychiatry journals, the abstracts are nearly always written in a manner that ensures that the conventional wisdom about psychiatric drugs isnt unduly threatened.

Now we have a new, powerful example of this institutional corruption at work.

As regular readers of Mad in America know, Donald Goff, Jeffrey Lieberman and others recently published a review of the long-term effects of antipsychotics in the American Journal of Psychiatry. Their conclusion was that while there is no good evidence that antipsychotics worsen long-term outcomes, there is good evidence supporting their long-term use. Joanna Moncrieff wrote a blog for MIA criticizing their study, as did Miriam Larsen-Barr, and I wrote a long ...

20:32

A Pediatrician Talks About the Dangers of Bullying Mad In America

From MinnPost: According to pediatrician Michael Pitt, M.D., pediatricians see a spike in suicide attempts at back-to-school time, in part due to anxiety over bullying at the launch of the school year. Pediatricians and parents should be aware of the impact of bullying and learn how to best support victims.

Article

20:31

What Happens When You Stop Taking Psychiatric Medications Mad In America

From Pacific Standard: A new study surveyed people who have come off psychiatric medications to come up with information doctors can use to help support their patients during the withdrawal process.

This is something people choose, and we dont know enough about it to help people, says Laysha Ostrow, chief executive officer of a mental-health consultancy in California and a public-health researcher who worked on the study. I feel that its important to bring those ideas into more of a mainstream conversation, given how many people decide to discontinue. It shouldnt be this subversive thing that we dont talk about in the health-care system or in research.'

Article

12:09

Mixed Lactobacillus plantarums strains inhibit Staphylococcus aureus induced inflammation and ameliorate intestinal microflora in mice. GreenMedInfo

PMID:  Biomed Res Int. 2017 ;2017:7476467. Epub 2017 Jul 27. PMID: 28819629 Abstract Title:  Mixed Lactobacillus plantarum Strains Inhibit Staphylococcus aureus Induced Inflammation and Ameliorate Intestinal Microflora in Mice. Abstract:  Objective. Staphylococcus aureus is an important pathogen that causes intestinal infection. We examined the immunomodulatory function of single and mixed Lactobacillus plantarum strains, as well as their impacts on the structure of the microbiome in mice infected with Staphylococcus aureus. The experiment was divided into three groups: protection, treatment, and control. Serum IFN- and IL-4 levels, as well as intestinal sIgA levels, were measured during and 1 week after infection with Staphylococcus aureus with and without Lactobacillus plantarum treatment. We used 16s rRNA tagged sequencing to analyze microbiome composition. IFN-/IL-4 ratio decreased significantly from infection to convalescence, especially in the mixed Lactobacillus plantarum group. In the mixed Lactobacillus plantarum group the secretion of sIgA in the intestine of mice (9.4-9.7ug/mL) was significantly higher than in the single lactic acid bacteria group. The dominant phyla in mice are Firmicutes, Bacteroidetes, and Proteobacteria. Treatment with mixed lactic acid bacteria increased the anti-inflammatory factor and the secretion of sIgA in the intestine of mice infected with Staphylococcus aureus and inhibited inflammation.

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11:45

Oral administration of Lactobacillus plantarum contributes to prevention of gut inflammation. GreenMedInfo

PMID:  Mol Med Rep. 2017 Aug 24. Epub 2017 Aug 24. PMID: 28849048 Abstract Title:  Lactobacillus plantarum LPOnlly alters the gut flora and attenuates colitis by inducing microbiome alteration in interleukin10 knockout mice. Abstract:  The association between inflammatory bowel disease (IBD) and gut microbes has been widely investigated. Our previous study demonstrated that Lactobacillus plantarum LPOnlly (LP) applied as a probiotic altered the gut flora and attenuated colitis in interleukin (IL)10 knockout (IL10/) mice. In the present study, metagenome sequencing was performed to investigate the gut microbiome in IL10/mice and the influence of oral administration of LPon microbial composition. Metagenomics sequencing was performed to investigate the influence of IBD on the gut microbiome with and without LP treatment. The alteration of the abundances of various taxonomic and functional groups were investigated across these gut microbiomes. The present study demonstrates that Akkermansia muciniphila was significantly enriched in IL10/ mice, and bacteroides were significantly increased following LP administration. In addition, the phylum Bacteroidetes and Firmicutes were significantly influenced by LP administration. Further characterization of functional capacity revealed that in the gut metagenomes of IL10/mice, genes encoding cell cycle control, replication, recombination, repair and cell envelope biogenesis were decreased, but intracellular trafficking, secretion, and vesicular transport were increased. The present findings indicate that the gut metagenome is associated with IBD, and oral administration of LP contributes to prevention of gut inflammation, providing insight into the treatment of IBD.

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11:21

Lactobacillus plantarum strains can enhance human mucosal and systemic immunity. GreenMedInfo

PMID:  Front Immunol. 2017 ;8:1000. Epub 2017 Aug 23. PMID: 28878772 Abstract Title:  Lactobacillus plantarum Strains Can Enhance Human Mucosal and Systemic Immunity and Prevent Non-steroidal Anti-inflammatory Drug Induced Reduction in T Regulatory Cells. Abstract:  Orally ingested bacteria interact with intestinal mucosa and may impact immunity. However, insights in mechanisms involved are limited. In this randomized placebo-controlled cross-over trial, healthy human subjects were given Lactobacillus plantarum supplementation (strain TIFN101, CIP104448, or WCFS1) or placebo for 7days. To determine whether L. plantarum can enhance immune response, we compared the effects of three stains on systemic and gut mucosal immunity, by among others assessing memory responses against tetanus toxoid (TT)-antigen, and mucosal gene transcription, in human volunteers during induction of mild immune stressor in the intestine, by giving a commonly used enteropathic drug, indomethacin [non-steroidal anti-inflammatory drug (NSAID)]. Systemic effects of the interventions were studies in peripheral blood samples. NSAID was found to induce a reduction in serum CD4(+)/Foxp3 regulatory cells, which was prevented by L. plantarum TIFN101. T-cell polarization experiments showed L. plantarum TIFN101 to enhance responses against TT-antigen, which indicates stimulation of memory responses by this strain. Cell extracts of the specific L. plantarum strains provoked responses after WCFS1 andTIFN101 consumption, indicating stimulation of immune responses against the specific bacteria. Mucosal immunomodulatory effects were studied in duodenal biopsies. In small intestinal mucosa, TIFN101 upregulated genes associated with maintenance of T- and B-cell function and antigen presentation. Furthermore, L. plantarum TIFN101 and WCFS1 downregulated immunological pathways involved in antigen presentation and shared downregulation of snoRNAs, which may suggest cellular destabilization, but may also be an indicator of tissue repair. Full sequencing of the L. plantarum strains revealed possible gene clusters that might be responsible for the differential biological effects of the bacteria on host immunity. In conclusion, the impact of oral consumption L. plantarum on host immunity is strain dependent and involves responses against bacterial cell components. Some strains may enhance specific responses against pathogens by enhancing antigen presentation and leukocyte maintenance in mucosa. In future studies and clinical settings, caution should be taken in selecting beneficial bacteria as closely related strains can have different effects. Our data show that specific bacterial strains can prevent immune stress induced by commonly consumed painkillers such as NSAID and can have enhancing beneficial effects on immunity of consumers b...

10:21

The current results suggest alcohol's potential involvement in malignant progression of breast cancer. GreenMedInfo

PMID:  Int J Oncol. 2017 Jan ;50(1):49-65. Epub 2016 Dec 9. PMID: 27959387 Abstract Title:  Long-term exposure of MCF-7 breast cancer cells to ethanol stimulates oncogenic features. Abstract:  Alcohol consumption is a risk factor for breast cancer. Little is known regarding the mechanism, although it is assumed that acetaldehyde or estrogen mediated pathways play a role. We previously showed that long-term exposure to 2.5 mM ethanol (blood alcohol ~0.012%) of MCF-12A, a human normal epithelial breast cell line, induced epithelial mesenchymal transition (EMT) and oncogenic transformation. In this study, we investigated in the human breast cancer cell line MCF-7, whether a similar exposure to ethanol at concentrations ranging up to peak blood levels in heavy drinkers would increase malignant progression. Short-term (1-week) incubation to ethanol at as low as 1-5 mM (corresponding to blood alcohol concentration of ~0.0048-0.024%) upregulated the stem cell related proteins Oct4 and Nanog, but they were reduced after exposure at 25 mM. Long-term (4-week) exposure to 25 mM ethanol upregulated the Oct4 and Nanog proteins, as well as the malignancy marker Ceacam6. DNA microarray analysis in cells exposed for 1 week showed upregulated expression of metallothionein genes, particularly MT1X. Long-term exposureupregulated expression of some malignancy related genes (STEAP4, SERPINA3, SAMD9, GDF15, KRT15, ITGB6, TP63, and PGR, as well as the CEACAM, interferon related, and HLA gene families). Some of these findings were validated by RT-PCR. A similar treatment also modulated numerous microRNAs (miRs) including one regulator of Oct4 as well as miRs involved in oncogenesis and/or malignancy, with only a few estrogen-induced miRs. Long-term 25 mM ethanol also induced a 5.6-fold upregulation of anchorage-independent growth, an indicator of malignant-like features. Exposure to acetaldehyde resulted in little or no effect comparable to that of ethanol. The previously shown alcohol induction of oncogenic transformation of normal breast cells is now complemented by the current results suggesting alcohol's potential involvement in malignant progression of breast cancer.

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10:13

RDW blood test: What It Means and What It Tells About Your Health Healthy and Natural World

Red cell distribution width (RDW for short) is a blood test used to measure the difference in size and volume of your red blood cells. Doctors use the RDW blood test as part of a complete blood test to help diagnose certain conditions that can affect your health. A blood test to measure variations in blood cell size can help diagnose causes of anemia, heart disease, diabetes, and liver disease.

The normal range for measuring the differences in the size of red blood cells (erythrocyte) is between 11.8% and 14.6%. RDW level greater than 14.5% means that there is a large degree of variation in red blood cell size. Elevated red blood cell distribution width could mean that a person is anemic and is at risk of other health conditions.

In this article, you will learn about the RDW blood test and what it means for your health. Using results from checking RDW level can help in the early diagnosis and successful treatment of certain health issues.

What is Red Cell Distribution Width (RDW) Blood Test?

RDW lab test is usually part of a complete blood count (CBC) and is used in conjunction with the MCV test results (or, red blood cell mean corpuscular volume) to tell about your health. Usually, a doctor will take the blood test if there are concerns that you have anemia.

According to Dr. Choladda Vejabhuti Curry on Medscape, the RDW results themselves wont confirm or rule out any type of anemia. Doctors will also take into account other indices on the complete blood test results like MCV and MCHC levels (mean corpuscular hemoglobin concentration).1

What are Low, Normal, and High RDW Levels?

According to doctors from the Mayo Clinic, the RDW reference range is 11.8% to 15.6%.2 However, some other clinics give the normal reference range for RDW between 11.6% and 14.6%. But, reference ranges may depend on the laboratory performing the test.3

The normal red blood cell distribution width in children will be slightly different. The RDW test results for children should be between 12% and 14% depending on their age.2

What RDW Blood Test Can Tell About Your Health

High and normal RDW levels in a blood test can help to tell a lot about your health. Taking RDW levels and comparing them with other red blood cell indices can allow doctors to check for anemia, vitamin B12 deficiency, low levels of iron, and other blood disorders.

According to Medscape, the RDW results from a blood test can help determine the cause of the anemia and, therefore, how to treat it. This is what RDW blood test results along with MCV results can tell about your health:4

Normal RDW and normal MCV. Normal levels of both the RDW and MCV parameters could mean that you h...

10:12

School and Hospital Grossly Overstep Their Bounds Restraining and Drugging Canadian 8 Year Old AGE OF AUTISM

When Debbie Kiroff's son disappeared from the teachers' sight, the school called police. But what happened next has her sounding the alarm about the appropriateness of both the school's and the hospital's response. (Submitted by Debbie Kiroff) NOTE: My father...

09:50

Proven Herbal Treatments for Crohns Disease GreenMedInfo

These evidence-based botanical medicines proven to induce or maintain remission in the debilitating inflammatory bowel disease known as Crohns offer hope to those resigned to a fate of life-altering immunosuppressive drugs or surgery.

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09:29

This review summarizes the preclinical results of Lactobacillus rhamnosus GG on cancer cells proliferation and tumor invasion. GreenMedInfo

PMID:  Front Pharmacol. 2017 ;8:603. Epub 2017 Sep 1. PMID: 28919861 Abstract Title:  Lactobacillus rhamnosus GG: An Overview to Explore the Rationale of Its Use in Cancer. Abstract:  Cancer is the second leading cause of death in the western world. In the era of precision medicine, a significant number of cancer patients can be cured with several anti-cancer therapeutic regimens. However, therapy failure may be caused by treatment side effects, such as diarrhea, especially occurring in patients with gastrointestinal or pelvic malignancies. In particular, diarrhea is one of the most frequent gastrointestinal toxicity during cancer treatment and it can result from nearly bot chemo- and radio-therapeutic strategies currently used. Diarrhea has a serious impact on patients' quality of life and treatment dosing and schedule modification due to its severity can negatively influence treatment outcomes. In this context, probiotics may play an interesting role in several human diseases with an inflammatory bowel involvement and, among these, Lactobacillus rhamnosus GG (LGG) is one of the most characterized and utilized. In particular, LGG is able to reverse intestinal dysbiosis and moderate diarrhea. Moreover, preclinical studies have documented its effects in reducing chronic inflammation associated with cancer development. This review summarizes the preclinical results of LGG on cancer cells proliferation and tumor invasion as well as the potential role of LGG use in cancer patients for the prevention and management of diarrhea associated with cancer treatment. Overall, these encouraging data support further investigation on the use of LGG in stratified patients undergoing specific therapeutic protocols, including chemotherapy and pelvic radiotherapy, in order to reduce the development of severe diarrhea and thus improve the adherence to the therapy and patients' quality of life.

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09:23

Link Fluoride Action Network

The results of the first ever US government funded study of fluoride/IQ have now been published. A team of researchers funded by the National Institutes of Health found that low levels of fluoride exposure during pregnancy are linked to significantly reduced IQ in children, according to a study published on September 19, 2017 in the journal Environmental Health Perspectives.

The study, entitled Prenatal Fluoride Exposure and Cognitive Outcomes in Children at 4 and 612 Years of Age in Mexico, was conducted by a team of scientists from University of Toronto, University of Michigan, Harvard, and McGill, and found:

higher levels of maternal urinary fluoride during pregnancy (a proxy for prenatal fluoride exposure) that are in the range of levels of exposure in other general population samples of pregnant women as well as nonpregnant adults were associated with lower scores on tests of cognitive function in the offspring at 4 and 612 y old.

Within hours of it being published, FAN released a video response featuring Chemist and Toxicologist, Professor Paul Connett, PhD.


TAKE ACTION NOW:

  1. Share FANs Facebook and...

09:00

NIH Supported Journal Publishes Landmark Study Linking Fluoride to Low IQ Fluoride Action Network

Increased levels of prenatal fluoride exposure have been linked to lower intelligence in children, according to the results of a new study.

In the eye-opening new peer-reviewed study, published on September 19, 2017, in the Journal of Environmental Health Perspectives, researchers found strong evidence of a link between fluoride and lower cognitive function in children.

With an impact factor of 9.78, Environmental Health Perspectives is one of the most highly ranked journals in Toxicology, Public, Environmental and Occupational Health, and Environmental Sciences.

The researchers found that higher levels of maternal urinary fluoride during pregnancy (a proxy for prenatal fluoride exposure) that are in the range of levels of exposure in other general population samples of pregnant women as well as nonpregnant adults were associated with lower scores on tests of cognitive function in the offspring at 4 and 612 y old, according to the study.

The study involved 1,576 samples taken from over 300 sets of mothers and children in Mexico by a research team from Toronto. The researchers tested the childrens cognitive development twice over the course of 12 years. In Mexico, Fluoride is not added to public water supply, but people are exposed through naturally occurring fluoride in water, toothpaste, fluoridated salt and other supplemental products.

Childhood exposure to fluoride is safer than prenatal. There is pretty good science now to support the fact that the fetal system tends to be more sensitive to environmental toxicants than once the child is born, said the studys lead author, Howard Hu, founding dean of the Dalla Lana School of Public Health at the University of Toronto, according to CNN.

The authors of the study looked for chemical markers in the urine of mothers and children, as previous studies attempted to measure fluoride exposure by analyzing environmental factors, such as water.

Since were using an integrated biological marker, it will give you a fairly standardized measure, Hu explained.

Interestingly, the study found significant effect with an increase in urine fluoride of 1mg/l being associated with a 5 to 6 point drop in IQ score. For perspective, the average fluoride intake in Mexican mothers was roughly the same as that of women in the United States.

The range of fluoride levels in Mexico also corresponded closely to the range found in most of the USA. The higher levels were similar to what is found in areas in the USA with fluoridated water, and the lower levels were similar to what is found in most unfluoridated parts of the USA, according to the...

08:52

Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model. GreenMedInfo

PMID:  Biomed Pharmacother. 2016 Oct ;83:536-541. Epub 2016 Jul 20. PMID: 27447122 Abstract Title:  Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model. Abstract:  BACKGROUND/AIM: Probiotics have been suggested as prophylactic measure in colon carcinogenesis. This study aimed at determining the potential prophylactic activity of Lactobacillus rhamnosus GG CGMCC 1.2134 (LGG) strain on colorectal carcinogenesis via measuring its effect on Nuclear factor kappa B (NFB) inflammatory pathway and apoptosis.MATERIALS AND METHODS: 64 Sprague Dawley rats were grouped into four as follows; Group 1 (Healthy control), Group 2 (LGG), Group 3 (cancer control Dimethyl hydrazine (DMH)) and Group 4 (LGG+DMH). LGG was administered orally to LGG and LGG+DMH groups. Colon carcinogenesis was chemically induced in LGG+DMH and DMH groups by weekly injection of 40mg/kg DMH. Animals were sacrificed after 25 weeks of experiment and tumor characteristics assessed. The change in expression of NFB-p65, COX-2, TNF, Bcl-2, Bax, iNOS, VEGF, -catenin, Casp3 and p53 were evaluated by western blotting and qRT-PCR.RESULTS: LGG treatment significantly reduced tumor incidence, multiplicity and volume in LGG+DMH treatment group compared to DMH cancer control group. Also, LGG treatment reduced the expression of-catenin and the inflammatory proteins NFB-p65, COX-2 and TNF; the anti-apoptotic protein Bcl-2, but increased the expression of the pro-apoptotic proteins Bax, casp3 and p53 compared with DMH group.CONCLUSION: LGG have a potential protection effect against colon carcinogenesis; inducing apoptosis and ameliorating inflammation, and may hold a promise as bio-therapeutic dietary agent.

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08:38

A review of probiotics in curing allergic and inflammatory conditions. GreenMedInfo

PMID:  Recent Pat Inflamm Allergy Drug Discov. 2016 Dec 26. Epub 2016 Dec 26. PMID: 28029082 Abstract Title:  Probiotics in Curing Allergic and Inflammatory Conditions - Research Progress and Futuristic Vision. Abstract:  BACKGROUND: Probiotics constitute the viable and beneficial microbes, which offer a dietary means to sustain the balance of gastro-intestinal (GI) microflora. Owing to their multiple health benefits, these have recently gained wide attention among researchers for exploring their potential in safeguarding the health of humans and animals. Probiotics could also modulate host-immune responses, thereby help in counteracting the immunological dysfunctions. Probiotics can inhibit the systemic invasion of pathogens entering through the GI mucosa/ oral cavity and have been found to possess effective prophylactic and therapeutic utilities against various infectious pathogens as well as non-infectious diseases and disorders.OBJECTIVE: The present review expedites the role of probiotics in curing the ailments related to allergic and inflammatory disease conditions.METHOD: A thorough reviewing of the literature and patents available on probiotics and their role in countering inflammation and allergy was conducted using authentic published resources available on Medline, Pubmed, Pubmed Central, Science Direct and other scientific databases. The information retrieved has been compiled and analysed pertaining to the theme of the study.RESULTS: Various micro-organisms have been evaluated for their probiotic efficacy, among these, the lactic acid bacteria viz. Lactobacillus sp. and Bifidobacterium sp. have extensively been studied and widely exploited. In the current post-globalized era of self and complementary medicines, the concept of probiotics and their therapeutic as well as prophylactic usage is gaining wide acceptance. As more and more bacterial strains are being proven for their pronounced influence on down regulation of immune regulation, atopic, inflammatory conditions, the use of probiotics is getting increased especially in the developed countries where such indications are high in prevalence. Apart from usage in immune related disorders, probiotics have been found to be effective in treating pouchitis, infantile diarrhoea due to infections, bacterial vaginosis, urinary tract infections, dental carries, diabetes, cancers as well augmenting the gut mucosal tolerance to various antibiotics and lactose intolerance.CONCLUSION: Present review gives an insight towards potent utility of this branch of beneficial microbial therapy in allergy and inflammations, which is still in the emerging phase and more scientific evidences need to be explored regarding exploration of the mechanisms of action, further experimental trials and validation of controlled clinical studies in humans a...

07:27

Probiotic lactobacillus had inhibitory effects of on the growth of human colonic carcinoma cell line HT-29. GreenMedInfo

PMID:  Molecules. 2017 Jan 10 ;22(1). Epub 2017 Jan 10. PMID: 28075415 Abstract Title:  Inhibitory Effects of Probiotic Lactobacillus on the Growth of Human Colonic Carcinoma Cell Line HT-29. Abstract:  This study was conducted to investigate the inhibitory effect of Lactobacillus cells and supernatants on the growth of the human colon cancer cell line HT-29. Our study results indicated that the PM153 strain exhibits the best adhesion ability and the highest survival in the gastrointestinal tract simulation experiment. Furthermore, after an 8-h co-culture of PM153 and HT-29 cells, the PM153 strain can induce the secretion of nitric oxide from the HT-29 cells. In addition, after the co-culture of the BCRC17010 strain (10 cfu/mL) and HT-29 cells, the Bax/Bcl-2 ratio in the HT-29 cells was 1.19, which showed a significant difference from the other control and LAB groups (p

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07:21

How the Mineral Boron found in Common Borax Helps Arthritis and Other Health Problems Health Impact News

Boron-Borax

How To Make Borax Solution. See video below.

by Paul Fassa
Health Impact News

Most of us are familiar with fluorides toxicity and capacity for negative effects, ranging from lowered IQ to  more serious neurological diseases and greater cancer risk. The type of fluoride added to our municipal tap water supplies is considered toxic industrial waste that the EPA banned from being dumped into our waterways and inland dumping sites.

Various health forums or chat sites discuss using the trace mineral boron as a solution for the fluorides in our bodies, but this health journalist didnt immediately trust using off the shelf Borax, a green cleaning solution, as a source of boron.

I was not willing to discuss this topic until I stumbled upon a more reliable, scientifically credentialed source, Dr. Newnham, PhD, DO, ND, who used boron to resolve his longstanding arthritic condition. His arthritic condition is not the only ailment addressed successfully using boron from Borax.

The Boron Revelations of Rex Newnham, PhD, DO, ND

Dr. Newnham was originally a professor of soil science and agricultural botany. After enduring the side effects of pharmaceutical drugs without improvement of his arthritic condition for years, he realized he needed to understand nutrition better to heal himself. So he earned degrees as an Osteopathic Doctor (DO) and Naturopathic Doctor (ND) with a Ph.D. in nutrition.

That training combined with his background in soil science led him to discover a trace mineral lacking in most food, due to poor soil conditions from modern farming methods. This trace mineral healed his arthritis boron.  In Australia where he lived and worked, natural boron compounds werent banned, but they were labeled as a poison.

Newnham argues that it is the amount that determines toxicity, not the compound itself. He used oxygen as an example. Breathing with 100 percent oxygen is rarely achieved, even so, too much oxygen well beyond the normal 21 percent we normally breathe for extended periods can actually kill. (Source)

After determining the toxicity zone of boron to be between 45 and 60 grams, which is quite a lot, Dr. Newnham used 30 milligrams of sodium tetraborate, aka Borax, as a daily dose of boron to finally cure his arthritis in three weeks.

Borax is a mined natural mineral compound that is high i...

07:14

Probiotics may be beneficial to prevent radiation-induced diarrhea in patients who suffered from abdominal or pelvic cancers. GreenMedInfo

PMID:  PLoS One. 2017 ;12(6):e0178870. Epub 2017 Jun 2. PMID: 28575095 Abstract Title:  Probiotics for prevention of radiation-induced diarrhea: A meta-analysis of randomized controlled trials. Abstract:  BACKGROUND: Radiotherapy is commonly used for abdominal or pelvic cancer, and patients receiving radiotherapy have a high risk developing to an acute radiation-induced diarrhea. Several previous studies have discussed the effect of probiotics on prevention of radiation-induced diarrhea, but the results are still inconsistent.OBJECTIVE: We performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the efficacy of probiotic supplementation for prevention the radiation-induced diarrhea.METHODS: Relevant RCTs studies assessing the effect of probiotic supplementation on clinical outcomes compared with placebo were searched in PubMed, EMBASE, and the Cochrane Library databases (up to March 30 2016). Heterogeneity was assessed with I2 and H2, and publication bias was evaluated using sensitive analysis.RESULTS: Six trials, a total of 917 participants (490 participants received prophylactic probiotics and 427 participants received placebo), were included in this meta-analysis. Compared with placebo, probiotics were associated with a lower incidence of radiation-induced diarrhea (RR: 0.55; 95% CI: 0.34-0.88; P = 0.01; I2: 87%; 95% CI: 75%-94%; H2: 2.8; 95% CI: 2.0-4.0). However, there is no significant difference in the anti-diarrheal medication use (RR: 0.68; 95% CI: 0.40-1.14; P = 0.14) or bristol scale on stool form (RR: 0.64; 95% CI: 0.35-1.17; P = 0.14).CONCLUSION: Probiotics may be beneficial to prevent radiation-induced diarrhea in patients who suffered from abdominal or pelvic cancers during radiotherapy period.

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07:11

Child Protective Services Failure A Tale of Two Boys Who Suffered Abuse Health Impact News

Union Station boys

Photo source: Dee Prince.

by Terri LaPoint
Health Impact News

They are a microcosm of the failures of the Child Protective Services System two young men whose stories clearly illustrate two sides of the same coin.

It was a chance encounter in the middle of Union Station in downtown Washington, D.C. As we talked with these young men, I realized that their stories were perfect demonstrations of why Dee Prince, Whitney Manning, and I joined hundreds of other parents and activists in our nations capitol for the Million Parent March events of September 17 19, 2017.

They, and hundreds of thousands of children with stories just like theirs, were why we were there. We dont even know their names, but their stories broke our hearts.

The green Mohawk initially drew our attention. Dee, a schoolteacher by trade, asked if we could have our picture made with them to post on Facebook.

The young men graciously obliged, and we had an impromptu photo shoot in the lobby of the train station. They are musicians and are obviously comfortable with such requests from strangers they meet on their way. We chatted a bit, and laughed together.

The tone shifted when we told them why we were there. We said that we were participating in the Million Parent March because we were fighting for families and children who have been torn apart by the child protective services system, family courts, and foster care.

Million Parent March 2017 mall

Million Parent March, September 18, 2017. Source.

Grew Up in the Foster Care System

A sadness came over the African-American gentlemans face, and he said softly that he was raised in the foster care system, and had been there since he was 3.

As an investigative journalist for the Health Impact News Medical Kidnap division, I have seen many patterns emerge from the stories I have researched. I told him that most of the former...

06:57

Probiotics lowered pro-inflammatory cytokines IL-6 in rheumatoid arthritis. GreenMedInfo

PMID:  Clin Rheumatol. 2017 Sep 15. Epub 2017 Sep 15. PMID: 28914373 Abstract Title:  The therapeutic effect of probiotics on rheumatoid arthritis: a systematic review and meta-analysis of randomized control trials. Abstract:  Rheumatoid arthritis is an autoimmune disease in which probiotics appears to have an immune modulating action along with decreased inflammatory process. Therefore, we aim to investigate the efficacy of probiotics as an adjuvant therapy for rheumatoid arthritis. A comprehensive literature search was performed using nine databases including PubMed and Web of Science. Interesting data was extracted and meta-analyzed. We assessed the risk of bias using Cochrane Collaboration's tool. The protocol was registered in PROSPERO (CRD 42016036769). We found nine studies involving 361 patients who met our eligibility criteria. Our meta-analysis indicated that pro-inflammatory cytokine IL-6 was significantly lower in the probiotics compared with the placebo group (standardized mean difference = - 0.708; 95% confidence interval (CI) - 1.370 to 0.047, P = 0.036). However, there was no difference between probiotics and placebo in disease activity score (mean difference 0.023; 95% CI - 0.584 to 0.631, P = 0.940). Probiotics lowered pro-inflammatory cytokines IL-6 in RA; however, its clinical effect is still unclear. Hence, many high-quality randomized controlled trials (RCTs) are still needed to prove this effect.

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06:25

Child Protective Services Failure A Tale of Two Boys Who Suffered Abuse Medical Kidnap

Union Station boys

Photo source: Dee Prince.

by Terri LaPoint
Health Impact News

They are a microcosm of the failures of the Child Protective Services System two young men whose stories clearly illustrate two sides of the same coin.

It was a chance encounter in the middle of Union Station in downtown Washington, D.C. As we talked with these young men, I realized that their stories were perfect demonstrations of why Dee Prince, Whitney Manning, and I joined hundreds of other parents and activists in our nations capitol for the Million Parent March events of September 17 19, 2017.

They, and hundreds of thousands of children with stories just like theirs, were why we were there. We dont even know their names, but their stories broke our hearts.

The green Mohawk initially drew our attention. Dee, a schoolteacher by trade, asked if we could have our picture made with them to post on Facebook.

The young men graciously obliged, and we had an impromptu photo shoot in the lobby of the train station. They are musicians and are obviously comfortable with such requests from strangers they meet on their way. We chatted a bit, and laughed together.

The tone shifted when we told them why we were there. We said that we were participating in the Million Parent March because we were fighting for families and children who have been torn apart by the child protective services system, family courts, and foster care.

Million Parent March 2017 mall

Million Parent March, September 18, 2017. Source.

Grew Up in the Foster Care System

A sadness came over the African-American gentlemans face, and he said softly that he was raised in the foster care system, and had been there since he was 3.

As an investigative journalist for the Health Impact News Medical Kidnap division, I have seen many patterns emerge from the stories I have researched. I told him that most of the former fos...

06:16

How to Eat Seasonally Without Sacrificing Health The Health Wyze Report - The Health Wyze Report

It's not a new concept. Both health and culinary experts alike have espoused the benefits of eating seasonally for decades. In-season foods tend to be more fresh and flavorful, offering distinctive advantages to both your overall wellbeing as well as your taste buds.

It seems simple, but eating seasonally can be tough in locales that experience harsh winters, or for individuals living within modest means. However, when done correctly, eating seasonally can be done throughout cold winter months, and on any budget.

06:15

Flu vaccine refusal healthcare worker Dumb Asses Skeptical Raptor

The Skeptical Raptor, stalking pseudoscience in the internet jungle.

Were nearing the commencement of the 2017-2018 flu season in the Northern Hemisphere. And every flu season, for the past 6 years, I reprint Dr. Mark Crislips epic rant about Dumb Ass healthcare workers who refuse to get the flu vaccine. Dr. Crislips hysterical characterizations, which were originally published in A Budget of Dumb Asses, are a list of the

Skeptical Raptor

06:02

If You Still Go to Starbucks Get Ready to Never Want to Again REALfarmacy.com

Source: If You Still Go to Starbucks Get Ready to Never Want to Again For more content like this visit REALfarmacy.com.

Every Dollar Spent at Starbucks Supports GMOs, Empowers Monsanto and Hurts Grassroots GMO Labeling Efforts. Heres What They Dont Want You to Know by ...

Source: If You Still Go to Starbucks Get Ready to Never Want to Again Learn more at REALfarmacy.com - Healthy News and Information.

04:42

Annona muricata leaves extracts prevent DMBA/TPA-induced skin tumorigenesis. GreenMedInfo

PMID:  Biomed Pharmacother. 2017 Oct ;94:481-488. Epub 2017 Aug 2. PMID: 28779710 Abstract Title:  Annona muricata leaves extracts prevent DMBA/TPA-induced skin tumorigenesis via modulating antioxidants enzymes system in ICR mice. Abstract:  Annona muricata, locally known as soursop has been reported to exhibit antiproliferative activities against various cancer cell lines. In this current study, we have investigated the antitumor promotion of various fractions of Annona muricata leaves (AML); hexane (AMLH), dichloromethane (AMLD) and methanol (AMLM) fraction respectively on 7, 12-dimethylbenz[]anthracene (DMBA) induced and 12-0-tetradecaboylphorbol-13-acetate (TPA) promoted skin tumorigenesis in mice via morphological assessment, biochemical analysis and histopathological evaluation. The results of the study revealed significant inhibition in tumor incidence, tumor burden and tumor volume in the groups received AMLH and AMLD, respectively, and suppressive effects in group received AMLM compared with carcinogen control group at week 21. Superoxide dismutase, catalase, and lipid peroxidation levels were returned to near normal by administration of AML to DMBA/TPA-induced mice. Theabove findings were supported by histopathological studies, in which the extensive epidermal hyperplasia in carcinogen control group was restored to normal in AML treated groups. Whilst, annonacin, a major annaonaceous acetogenin was found to be the highest in AMLH and AMLD. From the present study,it can be inferred that AML supressed DMBA/TPA-induced skin tumor and this antitumor-promoting activity may be linked to the antioxidant/free radical-scavenging constituents of the extract and annonacin contained in the extracts.

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04:25

Teen Girl Died on Vacation After She Drank This REALfarmacy.com

Source: Teen Girl Died on Vacation After She Drank This For more content like this visit REALfarmacy.com.

Energy drinks have becoming increasingly popular among youth in recent years. These drinks are found almost everywhere in a variety of flavors. There are ...

Source: Teen Girl Died on Vacation After She Drank This Learn more at REALfarmacy.com - Healthy News and Information.

04:12

Apple and blackcurrant polyphenol-rich drinks decrease postprandial glucose, insulin and incretin response to a high-carbohydrate meal in healthy men and women. GreenMedInfo

PMID:  J Nutr Biochem. 2017 Jul 27 ;49:53-62. Epub 2017 Jul 27. PMID: 28886437 Abstract Title:  Apple and blackcurrant polyphenol-rich drinks decrease postprandial glucose, insulin and incretin response to a high-carbohydrate meal in healthy men and women. Abstract:  Postprandial glycemic responses to meals are inhibited by polyphenol-rich plant foods. Combinations of polyphenols may be particularly effective through complementary mechanisms. A randomized, controlled, double-blinded cross-over trial was conducted in healthy volunteers to test the hypothesis that apple and blackcurrant polyphenol-rich drinks would reduce postprandial blood glucose concentrations. Secondary outcomes included insulin and glucose-dependent insulinotropic polypeptide (GIP) secretion. Twenty men (mean age 26 y, SD 8) and 5 postmenopausal women (mean age 57 y, SD 3) consumed a placebo drink (CON) and 2 polyphenol-rich drinks containing fruit extracts: either 1200 mg apple polyphenols (AE), or 600 mg apple polyphenols+600 mg blackcurrant anthocyanins (AE+BE), in random order with a starch and sucrose meal. Incremental areas under the curve (iAUC) for plasma glucose concentrations were lower following AE+BE over 0-30 and 0-120 min compared with CON; mean differences (95% CI) -32 mmol/Lmin (-41, -22, P

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03:48

Piperlongumine induces phase arrest and apoptosis in cholangiocarcinoma cells. GreenMedInfo

PMID:  Apoptosis. 2017 Sep 14. Epub 2017 Sep 14. PMID: 28913568 Abstract Title:  Piperlongumine induces G2/M phase arrest and apoptosis in cholangiocarcinoma cells through the ROS-JNK-ERK signaling pathway. Abstract:  Cholangiocarcinoma (CCA) is an aggressive, metastatic bile duct cancer. CCA is difficult to diagnose, and responds poorly to current radio- and chemo-therapy. Piperlongumine (PL) is a naturally-occurring small molecule selectively toxic to cancer cells by targeting reactive oxygen species (ROS). In this study, we demonstrated the potential anticancer activity of PL in CCA. PL markedly induced death in CCA cell lines in a dose- and time-dependent manner through the activation of caspase-3 and PARP. PL also stimulated ROS accumulation in CCA. Co-exposure of PL with the ROS scavenger N-acetyl-L-cysteine or GSH completely blocked PL-induced apoptosis in CCA cell lines. Increased p21 via the p53-independent pathway in PL-treated CCA cells led to G2/M phase arrest and cell apoptosis. In addition, the study showed that PL trigger CCA cell lines death through JNK-ERK activation. Furthermore, the different antioxidant capacity of CCA cell lines also indicates the susceptibility of the cells to PL treatment. Our findings reveal that PL exhibits anti-tumor activity and has potential to be used as a chemotherapeutic agent against CCA.

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03:20

The One Where Brian Deer Throws A Hissy Fit AGE OF AUTISM

By Ginger Taylor I am realizing that I need to narrow that down. The One Where Brian Deer Throws A Hissy Fit Threatening Miranda Baily For Saying That He Declined To Participate In Her Film, By Sending Her A Letter...

03:20

Piperine attenuates UV-R induced cell damage in human keratinocytes. GreenMedInfo

PMID:  J Photochem Photobiol B. 2017 Jul ;172:139-148. Epub 2017 May 19. PMID: 28550736 Abstract Title:  Piperine attenuates UV-R induced cell damage in human keratinocytes via NF-kB, Bax/Bcl-2 pathway: An application for photoprotection. Abstract:  Chronic ultraviolet radiation (UV-R) exposure causes skin disorders like erythema, edema, hyperpigmentation, photoaging and photocarcinogenesis. Recent research trends of researchers have focused more attention on the identification and use of photo stable natural agents with photoprotective properties. Piperine (PIP), as a plant alkaloid, is an important constituent present in black pepper (Piper nigrum), used widely in ayurvedic and other traditional medicines and has broad pharmacological properties. The study was planned to photoprotective efficacy of PIP in human keratinocyte (HaCaT) cell line. We have assessed the UV-R induced activation of transcription factor NF-B in coordination with cell death modulators (Bax/Bcl-2 and p21). The LC-MS/MS analysis revealed that PIP was photostable under UV-A/UV-B exposure. PIP (10g/ml) attenuates the UV-R (A and B) induced phototoxicity of keratinocyte cell line through the restoration of cell viability, inhibition ofROS, and malondialdehyde generation. Further, PIP inhibited UV-R mediated DNA damage, prevented micronuclei formation, and reduced sub-G1 phase in cell cycle, which supported against photogenotoxicity. This study revealed that PIP pretreatment strongly suppressed UV-R induced photodamages. Moleculardocking studies suggest that PIP binds at the active site of NF-B, and thus, preventing its translocation to nucleus. In addition, transcriptional and translational analysis advocate the increased expression of NF-B and concomitant decrease in IkB- expression under UV-R exposed cells, favouring the apoptosis via Bax/Bcl-2 and p21 pathways. However, PIP induced expression of IkB- suppress the NF-B activity which resulted in suppression of apoptotic marker genes and proteins that involved in photoprotection. Therefore, we suggest the applicability of photostable PIP as photoprotectiveagent for human use.

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03:17

Piperine attenuates UV-R induced cell damage in human keratinocytes. GreenMedInfo

PMID:  J Photochem Photobiol B. 2017 Jul ;172:139-148. Epub 2017 May 19. PMID: 28550736 Abstract Title:  Piperine attenuates UV-R induced cell damage in human keratinocytes via NF-kB, Bax/Bcl-2 pathway: An application for photoprotection. Abstract:  Chronic ultraviolet radiation (UV-R) exposure causes skin disorders like erythema, edema, hyperpigmentation, photoaging and photocarcinogenesis. Recent research trends of researchers have focused more attention on the identification and use of photo stable natural agents with photoprotective properties. Piperine (PIP), as a plant alkaloid, is an important constituent present in black pepper (Piper nigrum), used widely in ayurvedic and other traditional medicines and has broad pharmacological properties. The study was planned to photoprotective efficacy of PIP in human keratinocyte (HaCaT) cell line. We have assessed the UV-R induced activation of transcription factor NF-B in coordination with cell death modulators (Bax/Bcl-2 and p21). The LC-MS/MS analysis revealed that PIP was photostable under UV-A/UV-B exposure. PIP (10g/ml) attenuates the UV-R (A and B) induced phototoxicity of keratinocyte cell line through the restoration of cell viability, inhibition ofROS, and malondialdehyde generation. Further, PIP inhibited UV-R mediated DNA damage, prevented micronuclei formation, and reduced sub-G1 phase in cell cycle, which supported against photogenotoxicity. This study revealed that PIP pretreatment strongly suppressed UV-R induced photodamages. Moleculardocking studies suggest that PIP binds at the active site of NF-B, and thus, preventing its translocation to nucleus. In addition, transcriptional and translational analysis advocate the increased expression of NF-B and concomitant decrease in IkB- expression under UV-R exposed cells, favouring the apoptosis via Bax/Bcl-2 and p21 pathways. However, PIP induced expression of IkB- suppress the NF-B activity which resulted in suppression of apoptotic marker genes and proteins that involved in photoprotection. Therefore, we suggest the applicability of photostable PIP as photoprotectiveagent for human use.

read more

02:52

Do Avocados and Olive Oil Increase Your Intelligence? Natural Blaze

By Mae Chan

Consumption of monounsaturated fatty acids (MUFAs), found in olive oil, avocados and nuts, is linked to general intelligence according to a recent study in Neuroimage.

Fat intake, especially MUFAs have been shown to preserve HDL cholesterol and improve glycemic control, in diabetic patients, yet the exact sources are not been clearly defined.

A common misconception of olive oil is that it is high in fat and hence, should be avoided if you progress in any weight loss program. While it is true that olive oil is high in fat, it happens to be high in the right kinds of fat.

Same for avocadosthey contain naturally good fats; in fact over 75% of the fat in avoca...

02:30

To My Friends In Australia: The Vaccine War Deepens Natural Blaze

By Jon Rappoport

The string of abuses laid on citizens of Australia by their government grows almost week by week.

Now, parental rights to raise children, without interference from the State, is under a new form of attack. This must be resisted.

Schools are bringing doctors on board, as a permanent feature. Young children will be subjected to medical diagnoses and treatment, without consent or approval from parents, even if those parents actively object. The State is stealing the role of guardian.

The Herald Sun reports. Read carefully:

DOCTORS will have the power to treat students as young as 12 in schools even if parents refuse their consent.

GPs will consult at 100 Victoria high schools for up to one day a week as part of a $43.8 million program.

Guidelines released on Thursday show that even if a parent expressly states that a doctor should not [examine] their child, the GP can if they deem the teen mature enough.

Any student who wants to see the GP will be permitted to make an appointment, the policy said.

The GP will decide if the young person is mature enough to provide consent to any medical treatment for the prevailing issue.

...

02:22

Residents Forced to Buy Bottled Water As Coca-Cola Sucks Water Wells Dry Natural Blaze

By Matt Agorist

A world addicted to the consumption of chemical beverages with negative nutritional value responsible for filling hospital beds across Earth is quickly realizing this habit comes with a price outside of currency and health problems. Water. The residents of San Felipe Ecatepec, an Indigenous town three miles outside of San Cristobal de las Casas, Chiapas, in southern Mexico have watched their water wells literally dry up in only a few years thanks to Coca-Cola.

Juan Urbano, former president of the Communal Territory of San Felipe Ecatepec, says the water is drying up thanks to the peoples thirst for this chemical concoction known as Coca-Cola.

Many people dont drink pozol anymore, Urbano told Truth Out. Theyve replaced it with Coca-Cola. Pozol is a drink made from fermented corn dough that was popular among corn farmers and their communities. However, that is all changing.

In between San Felipe and the next town over, there lies a Coca-Cola bottling plant which, in order to keep up with demand consumed over 1.08 million gallons of water PER DAY just last year. 

As Truth Out reports:

San Felipe Ecatepec is one of thousands of towns across Mexico where corporate water consumption has taken precedence over local need. Advocates are scrambling to rein in a chain of public health consequences.

Chiapas has the highest renewable water resources per capita in all of Mexico. Yet, the tap water here is rarely safe to drink. And in rural Chiapas, more than...

02:08

Your Longevity May Be Based On How You Perceive Time Natural Blaze

By Josh Richardson

Time perception is a construction of the brain. How fast we perceive time to be passing or mind time can be manipulated or distorted. Evaluations of time differ based on our state of being at the time of judgment. How you age and how long you live may depend on that perception.

People tend to see their will as more determinant of future events than of past events. When we contemplate the future we feel as though we have a choice and are likely to influence events but when we consider our own past we often feel like most of the things that have happened were out of our control.

When people see that their actions are tied to what actually happens around them then their perceptions of free will change, or at the very least activated.

If youre bored or suffering, every second counts, and time seems to expand or slow down. When youre ecstatic, moments glitter right through your fingers.

Mind time also depends on your projected future state of being. If youre counting down to a root canal,...

01:30

A gut-wrenching experience: Authors retract, replace JAMA paper Retraction Watch

When economist Jason Hockenberry looked at data comparing some of the financial issues facing different U.S. hospitals, he was surprised by what he saw. Hockenberry was examining the effects of a recently introduced U.S. program that penalizes hospitals with relatively high rates of readmissions for certain conditions by reducing Medicare payments. Although Hockenberry expected hospitals []

The post A gut-wrenching experience: Authors retract, replace JAMA paper appeared first on Retraction Watch.

01:05

7 Reasons to Homestead: Why a Self Sufficient Lifestyle is Critical Today The Healthy Home Economist

homesteadingIf the numerous natural disasters in recent weeks have taught us anything, its that the more citizens are self sufficient, the better they fare when Mother Nature runs amok. When this self sufficiency is pursued as a lifestyle, it is known as homesteading.

Have you noticed that in the aftermath of unexpected and devastating disruptions to modern life, it is frequently the homesteaders who rise up as the everyday heroes? I know I have.

The Cajun navy is a great example of homesteaders in action. These are folks whose self sufficiency skills gave them the ability to reach out and and help others in need during the direst of circumstances.(...)
Read the rest of 7 Reasons to Homestead: Why a Self Sufficient Lifestyle is Critical Today (674 words)

The post 7 Reasons to Homestead: Why a Self Sufficient Lifestyle is Critical Today appeared first on The Healthy Home Economist.

00:38

Bega Valley: Fluoride deferral applauded as new reports presented to council Fluoride Action Network

There were cheers and applause in council chambers on Wednesday as councillors agreed to defer the vote on whether to fluoridate Bega Valley Shire water supplies.

The motion to defer followed three passionate presentations supported by community members in the gallery and included information on fluoride use in other countries.

Rob Slazenger, of Bermagui provided data relating to the use of of fluoride in a number of western industrialised countries which he said showed some of the the  non-fluoride users had better dental outcomes than those who did use it.

He also produced records from NSW Health of councils water fluoridation dosage data. There are four water supply systems in the Bega Valley Shire, Tantawanglo-Kiah, Brogo-Bermagui, Bemboka and Bega-Tathra. Fluoride has been added to the Bega-Tathra water supply system since 1963 and council is now considering adding fluoride to the Tantawanglo-Kiah and Brogo-Bermagui water supplies.

The data supplied by NSW Health appears to show gaps in record keeping and an extended period of overdosing between March and May 2010. A dose of 1 part per million (ppm) in water is recommended but overdosing varied from 30 to 97 per cent in the figures given to Mr Slazenger.

All presentations referenced the possibility of council referring the decision to NSW Health with speakers reminding council that it should be councillors own decision.

Greg Ferguson, of Pambula said a transfer of the decision to NSW Health would be a mockery of the democratic process.

Council would be tainted as gutless. The whole process has been a sham, Mr Ferguson said adding that the use of Hunter H2O as a community consultant was a gross conflict of interest.

It was a point not lost on councillor Russell Fitzpatrick who said he felt no obligation to transfer the matter to NSW Health.

I totally agree its a decision of this council. No way should there be an abrogation of our authority on this matter, Cr Fitzpatrick said to applause from the floor.

Director transport and utilities Terry Dodd mentioned the voluminous nature of material presented.

Given the number of comments it would be unreasonable to try and digest these today, Mr Dodds said and asked for time to review them.

*Original article online at http://www.begadistrictnews.com.au/story/4938818/fluoride-deferral-applauded-as-new-reports-presented-to-council/

00:26

Water authority to seek OK to add fluoridation equipment as soon as next week Fluoride Action Network

As early as next week, Meadville Area Water Authority will seek official approval to add fluoridation equipment, according to Tom Thompson of Gannett Fleming, MAWAs consulting engineer.

Thats what our goal is, Thompson said following Wednesdays MAWA board meeting.

The equipment design for fluoridation has been completed, Thompson told the board.

Although the board voted in June to fluoridate the water supplied by the authority to its customers, it must still seek a permit to do so from the state Department of Environmental Protection. At the time of the boards controversial 3-2 vote in favor of fluoridation, Ted Watts, the authoritys attorney, said that the permit approval process will involve additional public hearings.

Review of permit applications like MAWAs typically takes 120 business days about seven months according to Melanie Williams, DEP community relations coordinator.

Thompson said he already has attended a pre-application meeting with DEP representatives.

*Original article online at http://www.meadvilletribune.com/news/water-authority-to-seek-ok-to-add-fluoridation-equipment-as/article_f405b802-9e4b-11e7-8fa8-7b6f98f7058b.html

00:23

Petersburg: Citizens weigh in on water fluoridation Fluoride Action Network

Registered voters in Petersburg will be asked if the city should keep fluoride in its city water supply, and citizens are ratcheting up their stance on the issue from both sides.

Sandy Volk, a dental hygienist, regrets not giving her kids more fluoride vitamins when they were young.

Living near Papkes Landing, Volks household didnt receive city water, which had then and does now have a dose of fluoride in it. So she gave her kids fluoride compacted into a pill. She said the schools and recreation facilities all ran on city water, which her kids frequented, so she was careful not

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*Article online at http://www.petersburgpilot.com/story/2017/09/21/news/citizens-weigh-in-on-water-fluoridation/6473.html

00:12

Researchers urge caution over study linking fluoride exposure in pregnancy to lower IQs in children Fluoride Action Network

nti-fluoridation activists call it the biggest moment in the history of this whole debate. Its the response health policy experts and some of the authors themselves feared

Already there are people who claim fluoridated water is doing bad things to us. Now comes a new study suggesting a link between fluoride exposure in pregnancy and lower IQs in children.

Anti-fluoridation activists are calling it the biggest moment in the history of this whole debate and that any government that continues to add fluoride to tap water is condoning one huge, awful human experiment.

Its exactly the response health policy experts and some of the authors themselves feared.

There are some pretty bizarre theories out there, such as the idea that fluoride is being used to sedate the population, said University of Alberta health policy researcher Tim Caulfield.

I worry that this study which the authors note should be replicated, and they call for further analysis and research will be presented as definitive. It is not.

In what is being described as the first study of its kind and size exploring fluoride exposure and different stages of brain development, University of Toronto-led researchers analyzed data from 287 mother-child pairs in Mexico City. The study recruited pregnant women from 1994 to 2005, and has followed the women and their children since.

The researchers measured fluoride in archived urine samples taken from the women when they were pregnant, as well as from their children when they were between ages six and 12.

Next they looked at how levels of fluoride in urine related to how children scored on intelligence and neurocognitive function tests when they were four, and again when they were between six and 12.

Children scored 2.5 to three points lower on IQ tests for every 0.5 milligram-per-litre increase in their mothers urinary fluoride levels beyond 0.8 mg/L.

There was no clear association between IQ scores and values below 0.8 mg/L. As well, the childrens own urinary fluoride levels, measured when they were being tested, didnt seem to have a significant effect.

That suggests that whatever effect fluoride might have on brain development occurs in the womb.

In Canada and the U.S., most fluoride exposure comes from the fluoridation of drinking water to prevent cavities, and fluoride in toothpaste and other dental products.

In Mexico, not many people drink tap water, said Dr. Howard Hu, the studys principal investigator and founding dean of the University of Torontos Dalla Lana School of Public Health. Instead, the women were exposed to fluoridated salt. In 1991, that country became the seventh in the world to introduce a national salt fluoridation program to prevent cavities.

The researchers adjusted for numerous confounders,...

00:08

Survival Medicine Hour: Post-Irma, Floods, Shoulder Dislocation Doom and Bloom (TM)

Survival Medicine Hour #354 This Survival Medicine Hour 9/15: Hurricane Irma has wreaked havoc on Florida, Georgia, and South Carolina, and our hosts Joe and Amy Alton, aka Dr.Bones and Nurse Amy have now had two different homes survive destruction in a year: Their place in Gatlinburg on Ski Mountain, where 100 homes burned to the foundation last November as part of a huge human-set wildfire, and now their home in South Florida from Hurricane  Irmas winds. Well talk about

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Thursday, 21 September

23:53

American Dental Association Responds to Study Regarding Fluoride Intake in Mexico Fluoride Action Network

CHICAGO, September 19, 2017  The American Dental Association (ADA) examined a study in Environmental Health Perspectives based on fluoride intake in Mexico and concludes the findings are not applicable to the U.S. The intake of fluoride in Mexico is significantly different from the U.S. In Mexico, fluoride is added to salt (known as salt fluoridation) and it also exists naturally in varying degrees in community water. In the U.S., fluoride is not added to salt and it is only added to water in cases where the natural occurrence of fluoride is lower than the recommended level to prevent tooth decay. The ADA continues to endorse fluoridation of public water as the most effective public health measure to prevent tooth decay.

The authors of the study suggest that prenatal exposure to fluoride may cause lower IQ in children. However, because it is unknown how the subjects of the study ingested the fluoride whether through salt, water, or both no conclusions can be drawn regarding the effects of community water fluoridation in the U.S. Moreover, according to the ADA, the best available scientific evidence shows no association between the U.S.-recommended amount of fluoride used to prevent tooth decay and IQ.

More than 70 years of research and practical experience has shown that fluoridation is safe and effective. Fluoride helps prevent cavities in children and adults by making teeth more resistant to decay.

Fluoridation has been named by the Centers for Disease Control and Prevention as one of 10 great health achievements of the 20th century, and more than 100 U.S. and international health organizations including the World Health Organization recognize the public health benefits of community water fluoridation for preventing dental decay.

*Original press release online at http://www.ada.org/en/press-room/news-releases/2017-archives/september/ada-responds-to-study-regarding-fluoride-intake-in-mexico

23:35

Pro-Vaxxers Admit The Truth About the Function of Vaccines in America Well Just Get Rid Of All the Whites BolenReport

Anti-Vaxxers Discover SECRET Video Tapes Opinion by Deplorable Consumer Advocate Tim Bolen If you didnt own a gun before you read this article, and watch a short video, youll go get one, and learn how to use it, damn quick, to defend yourself and your family from the likes of Paul Offitt, Allison Singer, Dorit Continue reading Pro-Vaxxers Admit The Truth About the Function of Vaccines in America Well Just Get Rid Of All the Whites

The post Pro-Vaxxers Admit The Truth About the Function of Vaccines in America Well Just Get Rid Of All the Whites appeared first on BolenReport.

23:00

If you feel better, should you stop taking your antibiotics? Science-Based Medicine

A recent paper suggests that patients would be better off stopping antibiotics when they feel better, instead of completing the entire amount prescribed. Could this approach reduce antibiotic overuse and the risk of widespread resistance?

22:47

12 Different Studies Exploring the Anti-Cancer Properties of CBD Oil Natural Blaze

In 2016, the cannabis industry grew by 30 percent. But its relaxing properties are not the only reason for the interest in medical marijuana dispensary outlets across the US.

Research across the globe is all pointing to CBD oil as having high potential for fighting cancer on various levels. CBD is short for cannabidiol. CBD is a compound found in the cannabis plant, but without the psychoactive element that the THC strain has. This means CBD does not give you the high that most people think of when they hear of cannabis. But what does CBD do and why is it being heralded as the new miracle cure?

Here are 12 studies that show why CBD oil could be the best discovery to happen during our generation.

1. CBD restrains angiogenesis by various mechanisms.

In this study, researchers found that CBD inhibits the growth of various tumors. Its effect on both tumor and endothelial cells supports the speculation that CBD is an effective agent for treating cancer.

2. CBD generated anti-tumor activity in human breast carcinoma.

Researchers tested strains of cannabis to find what was the most effective in limiting cancer in breast carcinoma. CBD was found to be the...

22:42

RHEUMATISM THERAPY IS AN ACT OF BRAVERY Lyra Nara Blog

Rheumatism is a generic name for 200 different conditions characterized by inflammation and acute or chronic pain in muscles, joints, fibrous tissue. Although these 200 disorders defined by WHO have little in common in terms of their epidemiology, they do share three characteristics: they cause chronic, often intermittent acute pain, they are difficult to treat and are

22:38

New US Government Study on Fluoride Damage to Brain Fluoride Action Network

Fluoride Free New Zealand is calling on the 23 councils (out of the total of 67) that still fluoridate, to urgently implement a moratorium on fluoridation to protect the brains of children being born today in their community.

A major study published on Tuesday in the US Governments Environmental Health Perspectives has found that children born to mothers exposed to fluoride while pregnant, have significantly lower IQ scores. This is particularly relevant to New Zealand where half of the population is currently subjected to fluoridation.

The study measured fluoride in urine and found the average level of fluoride in urine was 0.9mg/L (mg/L = parts per million). To relate this to water fluoride concentration, a separate study found that pregnant women in an area with 0.4 to 0.8 ppm water fluoride only had slightly lower urine fluoride than the average participants in this study. The Ministry of Health recommends fluoride chemicals be added to the water at 0.85ppm.
Pregnant women in New Zealand in fluoridated areas likely have similar levels of urine fluoride as those in the Mexican study. Urine fluoride reflects total fluoride intake from all sources, not just fluoridated water. The paper also reports that in the USA, which is 70% fluoridated, urine fluoride ranges from about 0.5 to 1.5 mg/L which fully overlaps the range found in the Mexican study.
The child of a mother who was drinking water with 0.85ppm fluoride would be predicted to have 5 IQ lower IQ points than if the mother had drunk water with close to zero fluoride in it. This obviously has huge consequences for New Zealand children.

The Ministry of Health recommended 1ppm until the 1990s when it reduced to a range from 0.7ppm to 1ppm, with a target of 0.85ppm. The US Human and Health Services have directed a maximum of 0.7ppm for fluoridation.

This study was very carefully done by a group of researchers who have produced over 50 papers on the cognitive health of children in relationship to environmental exposures.  It was funded by the US Governments National Institute of Health and was a multi-million dollar study.  This was the groups first study of fluoride their other studies mostly dealing with lead, mercury and other environmental neurotoxicants.

This study controlled for a wide range of potential factors that might have skewed the results and produced a false effect.  It was able to largely rule out confounding effects by these other factors.  The factors ruled out included lead, mercury, socio-economic status, smoking, alcohol use, and health problems during pregnancy.

This study offers confirmation of previous studies in Mexico, China and elsewhere.  Some of those studies had higher fluoride exposures than are commonly found in fluoridating countries, but many did not.  The sole study in a co...

22:30

Surgery journal retracts two papers it didnt mean to publish Retraction Watch

The Annals of Surgery has retracted two papers it never intended to publish. According to journals editor, Keith Lillemoe, the paperspublished in 2015, two months aparthad undergone full peer review and were rejected, like 90% of submissions to our journal: The decision was clear and the authors were notified. But somehow, Lillemoe said, our publishing []

The post Surgery journal retracts two papers it didnt mean to publish appeared first on Retraction Watch.

22:27

Fluoride OKd for Albuquerque water supply Fluoride Action Network

Fluoride again will be added to Albuquerques water supply.

Water utility board members voted 5-2 Wednesday to approve a $250,000 appropriation that will allow the Albuquerque Bernalillo County Water Utility Authority to buy the equipment needed to resume supplemental drinking-water fluoridation, which the utility halted in 2011.

The decision followed nearly an hour of passionate pleas by both opponents and supporters of fluoridation similar to comments expressed at two earlier public hearings on the issue.

At the end of the day, when theres a question about science, we need to listen to the scientists, board member and Albuquerque City Councilor Pat Davis said before he voted in favor of resuming fluoridation. Davis withdrew his proposal for an advisory question on the 2018 general election ballot that would have asked Bernalillo County voters whether they support or oppose supplemental fluoridation.

Voting against the appropriation were Albuquerque Councilors Klarissa Pea and Trudy Jones. Joining Davis in support were Bernalillo County Commissioners Debbie OMalley, Wayne Johnson and Maggie Hart Stebbins and Albuquerques Chief Administrative Officer Rob Perry, who represents Mayor Richard Berry on the board.

Im just philosophically opposed to this, Jones said in explaining her opposition to fluoridation. I dont think at any time the government should add something to our water if some people dont want it.

Jones remarks echoed those of several opponents who told the board that people who want fluoride can obtain it from commercial products such as toothpaste and mouthwash and from fluoride treatments provided by dentists, but the water utility shouldnt force fluoride on people who believe they are harmed by it.

There are health concerns that people talked about, Pea said. For people with kidney disease theres a lot of concern about fluoride.

Pea also said she was troubled that supporters pitch drinking water fluoridation as a way of helping low-income children. To me its an assumption that lower-income children dont brush their teeth, she said.

The measure approved Wednesday requires the utility to maintain fluoride levels between 0.65 and 0.72 milligrams per liter in the public water supply.

Fluoride is a mineral found naturally in Albuquerques water supply at levels of about 0.4 to 0.5 milligram per liter, according to a report prepared by the utility staff.

The city began supplemental fluoridation in 1972, but ended the practice in 2011 while federal officials considered new recommendations about fluoridation levels.

In 2015, the U.S. Public Health Service updated the federal drinking water standards, recommending that community water systems add fluoride to 0.7 milligrams per liter to prevent tooth decay. That recommendation prompted the utility to reconsider fluoridation during budget discussions earlier t...

22:25

New Nitrogen trifluoride plant built in China. Gas used to etch silicon wafers Fluoride Action Network

Excerpt:

Hyosung constructed a nitrogen trifluoride plant with the capacity of 13 million tons in March and a spandex plant with the capacity of 16,000 tons in May, both in Quzhou County, China. Nitrogen trifluoride is gas used to etch silicon wafers. Hyosungs advance to China was what Cho Hyun Joon Chairman intended. Hyosung Cho Hyun Joon Chairman said, We must target the Chinese market first to be the world No. 1 in spandex business. He formed Team Project C in the late 1990s and led its penetration into the market. C stands for China. China subsidiaries carry out localization strategy by appointing local employees to major positions across all business processes including production, marketing and purchase, a Hyosung official said. They have served as a role model for all other Hyosung production bases built worldwide later.

*Original article titled, Hyosung Cho Hyun Joon Chairman Targets the Global Market with ICT and Localization, online at http://www.businesswire.com/news/home/20170920006432/en/Hyosung-Cho-Hyun-Joon-Chairman-Targets-Global

22:09

You Can 'Pick Up' A Good or Bad Mood From Your Friends PreventDisease.com

New research suggests that both good and bad moods can be picked up' from friends, but depression can't.

21:57

Vaccines and Blue Foot Syndrome Vaxxter

By Dr. Sherri Tenpenny, DO, AOBNMM, ABIHM I grow weary of people who continually demand proof that vaccines cause harm and do cause autism. Every year the insistence for More research!! More research! goes by,...

The post Vaccines and Blue Foot Syndrome appeared first on Vaxxter.

21:48

Mainstream Science Site Admits Flu Shot Fails Vaxxter

The annual contemplation over why the flu shot consistently fails is making headlines again. This time, the folks at Science Magazine have created an article and video over the shots consistent failures to protect people...

The post Mainstream Science Site Admits Flu Shot Fails appeared first on Vaxxter.

20:33

Psychiatry Ignores an Elephant in the Room Mad In America

Large cohort studies of people with a first-episode psychosis provide a unique opportunity for finding out why so many young people with schizophrenia spectrum disorders die at a young age. However, it seems that those psychiatrists who have access to the mortality data generally do not want the facts to come out. In published cohort studies, there is virtually always too little information or no information at all about the causes of death.

In 2012, Hegelstad et al. published 10-year follow-up data for 281 patients with a first-episode psychosis (the TIPS study). 1 Although their average age at entry into the study was only 29 years, 49 patients (17%) had died in less than 10 years. The authors detailed article was about recovery and symptom scores and they took no interest in all these deaths, which appeared in a flowchart of patients lost to follow-up and were not commented upon anywhere in their paper. In the text, however, they mentioned only 28 deaths (11%), so it is difficult to know how many died.

On March 5th 2017, I wrote to the first author: In your interesting study from 2012, Long-Term Follow-Up of the TIPS Early Detection in Psychosis Study: Effects on 10-Year Outcome, 28 patients died of 281. Do you have the causes of death, which would be very interesting to know about? I noticed that most patients were still on antipsychotics 10 years after they started (table 2). I consider this very frightening, e.g. around half of them will have tardive dyskinesia (which is often masked by ongoing treatment) and many, if not all, will have developed permanent brain damage at this point, to mention just two of the important harms of long-term treatment. In contrast, only 17% of patients in Lappland were still on antipsychotics 5 years after their first episode (compared to 75% in Stockholm).

I sent a reminder ten days later and was told I would get an answer shortly. On May 10th, I wrote again: It is now another two months. You did an important study and it is important for the world to know what 10% of your very young patients died from in just 10 years. It is a frightening death rate. Do we need to file a Freedom of Information request to get this information?

Hegelstad replied that, We are preparing a manuscript detailing the information you are asking for. It will be submitted to a peer-reviewed journal. When published the information will be readily available to all.

The preparation of the manuscript and its publication were very fast. Already in June, the paper was out, in World Psychiatry.2 With this record speed, I wondered what the peer review had been like, if there was any. It looked more like a letter to the editor, with no subheadings, and taking up...

20:33

Renowned Psychiatrist Warns That Trump is a Danger to Us All Mad In America

From Alternet: A new book, The Dangerous Case of Donald Trump, written by 27 psychiatrists, psychologists, and mental health experts to warn the public of President Trumps dangerousness, will be published on October 3rd. According to Robert Jay Lifton, who wrote the books foreword, The Goldwater Rule is subordinate mental health professionals duty to warn people in danger and protect human life and well-being.

Article

20:32

Marijuana Research: Overcoming the Barriers Mad In America

From APA Science Advocacy: As an increasing number of states are beginning to legalize the medicinal and/or recreational use of marijuana, it is clear that more research is needed on the risks and potential benefits of the drug. The American Psychological Association is working for legislation that will remove some of the major barriers preventing scientists from pursuing the full range of research necessary to understand the impact of marijuana.

Article

20:31

Coroner Finds Anti-Smoking Drug Contributed to Mans Suicide Mad In America

From ABC: A Queensland Coroner has found that the anti-smoking drug Champix played a role in the suicide of a 22-year-old man, Timothy John, who died in April 2013.

Article

20:30

Liar, Healer, Monster, Savior. The Pathological Optimist. A New Movie. AGE OF AUTISM

Premiering at the Angelika Film Center September 29th, The Pathological Optimist by filmmaker Miranda Bailey about Dr. Andrew Wakefield, one of the producers of Vaxxed: From Cover-Up to Catastrophe. The Pathological Optimist explores the controversial Andrew Wakefield, who was stripped...

15:30

What Can Sweet Fennel Oil Do for Your Health? Articles

What Is Sweet Fennel Oil?

Sweet fennel oil comes from crushed fennel seeds (Foeniculum vulgare). The plant, which is a part of the Apiaceae family including carrots or parsley, 1 has an herby, slightly spicy smell that resembles aniseed. It is native to Southern Europe, but is also now grown in parts of Northern Europe, Australia and North America. 2

Uses of Sweet Fennel Oil

Fennel was used in various ancient civilizations by the Egyptians for food and medicine and by the Chinese as a remedy for snake bites. During the Middle Ages, it was hung over doorways to drive away evil spirits.

In present times, sweet fennel oil is used mostly for medicinal purposes, such as killing parasitic worms and their spores in the intestines and excretory tracts and as a laxative with no side effects. It is also used for cosmetic purposes, especially as an ingredient in massage oils,3 perfumes, toothpastes and soaps.4

Composition of Sweet Fennel Oil

The chemicals found in sweet fennel oil include anethole, fenchone, estragole, a-pinene and -pinene, a-phellandrene and -phellandrene, a-Terpineol, myrcene, campfer and para-Cymol.5

Benefits of Sweet Fennel Oil

Sweet fennel oil acts as a stimulant for the nervous, digestive and excretory system and the endocrine and exocrine glands. It helps relieve dizziness, fatigue and exhaustion.6 Other benefits you can get from using sweet fennel oil include:

Carminative: eases indigestion and stomach pain

Diuretic: removes excess water, sodium, uric acid, bile salts and other toxic elements

Splenic: protects the spleen from various infections

Depurative: removes toxic substances in the blood

Expectorant: provides relief from mucus and phlegm that lead to congestion of the nasal tract, pharynx, bronchi and lungs

Emmenagogue: relieves painful dysmenorrhea and helps prevent untimely or premature meno...

The Danger of Undiagnosed Sleep Apnea Articles

By Dr. Mercola

Lack of sleep and poor quality of sleep have been linked not only to absentmindedness and accidents, but also to serious health risks such as Alzheimer's disease, diabetes, heart disease and obesity. More than ever, Americans are sleeping less and suffering because of it. Of the many reasons you may be sleep deprived, one of the most dangerous is sleep apnea.

If you are among the 22 million Americans suffering from mild to moderate sleep apnea,1 your sleep may be punctuated by loud snoring, snorts or choking sounds that result from periodic disruptions to your breathing. Depending on the severity of your condition, these breath interruptions may occur just a few times or hundreds of times an hour. During these moments without breath, your brain and the rest of your body is literally being starved of oxygen.

Typically, normal breathing starts again as you gasp for air, resulting in the loud snorts or choking sounds often reported by your sleep partner. While most people consider snoring to be a normal occurrence, or a source of entertainment given the funny noises associated with it, sleep apnea is no laughing matter.

It is a serious health disorder that can be dangerous, and even life-threatening, when untreated. Notably, an estimated 80 percent moderate and severe obstructive sleep apnea cases go undiagnosed.2 If you think you or someone you love may be suffering from sleep apnea, take action today to pursue a diagnosis and treatment. In doing so, you will be on your way to a better night's sleep and significantly improved health.

The Importance of Sleep

According to the Centers for Disease Control and Prevention,3 lack of sleep is a major public health problem, and insufficient sleep has been linked to a wide range of health problems. After reviewing more than 300 studies to determine how many hours of sleep most people need to maintain their health, an expert panel concluded that most adults need around...

Empathy: Caring for Others Is Good for You Articles

By Dr. Mercola

Empathy, the ability to put yourself in someone elses shoes, so to speak, and understand their feelings and point of view, is a character trait that may benefit society and individuals in multiple ways. Empathy training has been found to reduce stress levels among medical students facing intense emotional encounters with patients, for example.1 While many parents try to instill empathetic qualities in their children, theres growing research that empathy has deep neurological roots in humans.

One of the first signs that empathy may be ingrained in all of us occurred in 1848, when a foreman named Phineas Gage working on a railroad construction project had an accident, which resulted in an iron rod going through his skull. He survived, but not without marked changes to his personality. His friends, family and physician described him as rude and inconsiderate following the accident.2

The Neurological Side of Empathy

The term empathy didnt come to be for another six decades after Gages accident, but what the accident essentially took from the foreman was the ability to feel empathy. In 1994, researchers were able to take measurements from Gages skull and use modern neuroimaging techniques to recreate the accident and determine its effects on his brain.

The damage involved both left and right prefrontal cortices in a pattern that, as confirmed by Gage's modern counterparts, causes a defect in rational decision making and the processing of emotion, researchers concluded.3

Injury was found to have occurred in the ventromedial prefrontal cortex (vMPFC), which is one of 10 brain regions now known to be involved in empathy. In his book Zero Degrees of Empathy, Simon Baron-Cohen, professor of developmental psychology at the University of Cambridge in the United Kingdom, describes the complex neurological underpinnings of empathy, revealing the many ways our brains help us to care about other people:4

  • The medial frontal cortex has been linked to social cognition, which allows people to be part of a social group and process information about others5
  • The inferior frontal gyrus (IFG) may be involved in recognizing emotions on faces6
  • More activity in the IFG when people look at emotional expressions is linked to higher scores on the empathy quotient scale...

14:14

Piperine promoted beneficial metabolism during exercise by regulating carbohydrate, fat metabolism and redox signals. GreenMedInfo

PMID:  Nutr Metab (Lond). 2017 ;14:43. Epub 2017 Jul 4. PMID: 28680454 Abstract Title:  Piperine enhances carbohydrate/fat metabolism in skeletal muscle during acute exercise in mice. Abstract:  BACKGROUND: Exercise promotes energy metabolism (e.g., metabolism of glucose and lipids) in skeletal muscles; however, reactive oxygen species are also generated during exercise. Various spices have been reported to have beneficial effects in sports medicine. Here, we investigated the effects of piperine, an active compound in black pepper, to determine its effects on metabolism during acute endurance exercise.METHODS: ICR mice (n = 18) were divided into three groups: nonexercise (CON), exercise (EX), and exercise with piperine (5 mg/kg) treatment (EP). Mice were subjected to enforced exercise on a treadmill at a speed of 22 m/min for 1 h. To evaluate the inflammatory responses following exercise, fluorescence-activatedcell sorting analysis was performed to monitor changes in CD4(+) cells within the peripheral blood mononuclear cells (PBMCs) of mice. The expression levels of metabolic pathway components and redox-related factors were evaluated in the soleus muscle by reverse transcription polymerase chain reaction and western blotting.RESULTS: There were no changes in the differentiation of immune cells in PBMCs in both the EX and EP groups compared with that in the CON group. Mice in the EX group exhibited a significant increase in the expression of metabolic pathway components and redox signal-related components compared with mice in the CON group. Moreover, mice in the EP group showed greater metabolic (GLUT4, MCT1, FAT/CD36, CPT1, CS) changes than mice in the EX group, and changes in the expression of redox signal components were lower in the EP group than those in the EX group.CONCLUSION: Our findings demonstrate that piperine promoted beneficial metabolism during exercise by regulating carbohydrate/fat metabolism and redox signals. Therefore, piperine may be a candidate supplement for improvement of exercise ability.

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13:58

Piperine can enhance the antioxidant and anti-inflammatory properties of quercetin. GreenMedInfo

PMID:  Neural Regen Res. 2017 Jul ;12(7):1137-1144. PMID: 28852397 Abstract Title:  Neuroprotective potential of Quercetin in combination with piperine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. Abstract:  1-Methy-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin that selectively damages dopaminergic neurons in the substantia nigra pars compacta and induces Parkinson's like symptoms in rodents. Quercetin (QC) is a natural polyphenolic bioflavonoid with potent antioxidant and anti-inflammatory properties but lacks of clinical attraction due to low oral bioavailability. Piperine is a well established bioavailability enhancer used pre-clinically to improve the bioavailability of antioxidants (e.g., Quercetin). Therefore, the present study was designed to evaluate the neuroprotective potential of QC together with piperine against MPTP-induced neurotoxicity in rats. MPTP (100g/L/rat, bilaterally) was injected intranigrally on days 1, 4 and 7 using a digital stereotaxic apparatus. QC (25 and 50 mg/kg, intragastrically) and QC (25 mg/kg, intragastrically) in combination with piperine (2.5 mg/kg, intragastrically) were administered daily for 14 days starting from day 8after the 3(rd) injection of MPTP. On day 22, animals were sacrificed and the striatum was isolated for oxidative stress parameter (thiobarbituric acid reactive substances, nitrite and glutathione), neuroinflammatory cytokine (interleukin-1, interleukin-6, and tumor necrosis factor-) and neurotransmitter (dopamine, norepinephrine, serotonin, gamma-aminobutyric acid, glutamate, 3,4-dihydroxyphenylacetic acid, homovanillic acid, and 5-hydroxyindoleacetic acid) evaluations. Bilateral infusion of MPTP into substantia nigra pars compacta led to significant motor deficits as evidenced by impairments in locomotor activity and rotarod performance in open field test and grip strength and narrow beam walk performance. Both QC (25 and 50 mg/kg) and QC (25 mg/kg) in combination with piperine (2.5 mg/kg), in particular the combination therapy, significantly improved MPTP-induced behavioral abnormalities in rats, reversed the abnormal alterations of neurotransmitters in the striatum, and alleviated oxidative stress and inflammatory response in the striatum. These findings indicate that piperine can enhance the antioxidant and anti-inflammatory properties of QC, and QC in combination with piperine exhibits strong neuroprotective effects against MPTP-induced neurotoxicity.

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13:28

Quercetin can be a suitable therapeutic agent to prevent neurodegeneration in diabetic retinopathy. GreenMedInfo

PMID:  Saudi J Biol Sci. 2017 Sep ;24(6):1186-1194. Epub 2016 Dec 3. PMID: 28855811 Abstract Title:  Neuroprotective effects of quercetin in diabetic rat retina. Abstract:  Diabetic retinopathy (DR) is a severe complication of diabetes and the leading cause of blindness among working adults worldwide. DR is being widely recognized as a neurodegenerative disease of the retina, since, retinal neurons are damaged soon after diabetes onset. Diabetes-induced oxidative stress is considered as central factor that dysregulates neurotrophic factors and activates apoptosis, thereby damages neurons in the diabetic retina. Flavonoids being a powerful antioxidant have been considered to protect neurons in diabetic retina. The purpose of this study was to analyze the beneficial effects of flavonoid, quercetin to protect neurons in the diabetic rat retina. We quantitated the expression levels of BDNF, NGF, TrkB, synaptophysin, Akt, Bcl-2, cytochrome c and caspase-3 using Western blotting techniques in the diabetic retina with and without quercetin treatments and compared with non-diabetic rats. In addition, we employed ELISA techniques to determine the level of BDNF. Caspase-3 activity and the level of glutathione were analyzed by biochemical methods. Our results indicate that quercetin treatment to diabetic rats caused a significant increase in the level of neurotrophic factors and inhibited the level of cytochrome c and caspase-3 activity in the diabetic retina. Furthermore, the level of an anti-apoptotic protein Bcl-2 was augmented in quercetin treated diabetic retina. Thus, quercetin, may protect the neuronal damage in diabetic retina by ameliorating the levels of neurotrophic factors and also by inhibiting the apoptosis of neurons. Therefore, this study suggests that quercetin can be a suitable therapeutic agent to prevent neurodegeneration in diabetic retinopathy.

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13:10

Quercetin application attenuated mucosal damage from ischemia reperfusion injury by inhibiting neutrophil infiltration. GreenMedInfo

PMID:  Biomed Pharmacother. 2017 Aug 28 ;95:346-354. Epub 2017 Aug 28. PMID: 28858733 Abstract Title:  Quercetin attenuates the ischemia reperfusion induced COX-2 and MPO expression in the small intestine mucosa. Abstract:  Quercetin, the active substance of tea, fruits and vegetables, exerts a broad spectrum of pharmacological activities and is considered to have potential therapeutic application. The present study was designed to investigate the beneficial effect of quercetin against experimental ischemia- reperfusion (IR) injury of the small intestine in rats. Quercetin was administrated intraperitoneally 30min before 1h ischemia of superior mesenteric artery with following reperfusion periods lasting 1, 4 and 24h. The male specific pathogen-free Charles River Wistar rats were used (n=45). In acute phase, 4h after start of reperfusion, the quercetin induced a significant decrease in mucosal injury index (p

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12:55

Low concentration of quercetin antagonizes the invasion and angiogenesis of human glioblastoma U251 cells. GreenMedInfo

PMID:  Onco Targets Ther. 2017 ;10:4023-4028. Epub 2017 Aug 11. PMID: 28860810 Abstract Title:  Low concentration of quercetin antagonizes the invasion and angiogenesis of human glioblastoma U251 cells. Abstract:  Glioblastoma is the most aggressive type of brain tumor with a very poor prognosis. Therefore, it is always of great importance to explore and develop new potential treatment for glioblastoma. Quercetin, a flavonoid present in a variety of human foods, has been shown to inhibit various tumor cell proliferation. In this study, we found that treating human glioblastoma U251 cells with 10g/mL quercetin for 24 hours, a concentration that was far below the IC50 (113.65 g/mL) and at which quercetin failed to inhibit cell proliferation, inhibited cell migration (30%) and cell invasion as examined by wound scratch assay and transwell assay, respectively. We further showed that 10 g/mL quercetin inhibited cell migration and tube formation of human umbilical vein endothelial cells induced by the conditioned medium derived from U251 cell culture. The inhibitory effect of quercetin on migration and angiogenesis is possibly mediated through the downregulation of protein levels ofVEGFA, MMP9, and MMP2 as detected by Western blot. Our findings demonstrated that low concentration of quercetin antagonized glioblastoma cell invasion and angiogenesis in vitro.

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12:39

Quercetin reduces neural tissue damage and promotes astrocyte activation after spinal cord injury in rats. GreenMedInfo

PMID:  J Cell Biochem. 2017 Sep 2. Epub 2017 Sep 2. PMID: 28865131 Abstract Title:  Quercetin reduces neural tissue damage and promotes astrocyte activation after spinal cord injury in rats. Abstract:  Spinal cord injury (SCI) is lead to locomotor impairment because of neurological damage after following trauma. Quercetin (Que) has been confirmed have a neuro-protective effect during nerve damage processes. The purpose of this study was to determine the roles of Que in functional recovery, cavity formation, astrocyte activation and nerve regeneration following SCI. Sprague-Dawley rats were randomly divided into 3 groups: Sham group, SCI group and Que+SCI group. A rat model of SCI was made at T10 using the modified Allen's method. In the Que+SCI group, animals underwent laminectomy and were then intraperitoneally injected with 20mg/kg Que for 7 days. Locomotor function was determined with the Basso, Beattie, Bresnahan (BBB) scoresat 1, 3, 5 and 7 days post injury. At 7 days post injury, somatosensory evoked potentials (SEPs) and motor evoked potentials (MEPs) were recorded. Hematoxylin-Eosin (HE) staining was used to investigate cavity formation. Astrocyte activation was assayed by immunohistochemistry staining with an antibody specific for glial fibrillary acidic protein (GFAP), as well as the expression of GFAP and S100. Axons were stained using an antibody specific for neurofilament 200 (NF200) and 5-hydroxytryptamine (5-HT). In addition, the protein level of BDNF, p-JNK2 and p-STAT3 was detected using western blot. Que promoted locomotor function and electrophysiological recovery, reduced cavity formation, contributed to astrocyte activation and axonal regeneration after acute SCI. Moreover, Que up-regulated the expression of BDNF, but reduced p-JNK2 and p-STAT3 expression after acute SCI. Taken together,Que promoted locomotor and electrophysiological functional recovery, astrocyte activation and axonal regeneration after acute SCI, possibly through BDNF and JAK2/STAT3 signaling pathways. This article is protected by copyright. All rights reserved.

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12:17

Quercetin attenuates manganese-induced neuroinflammation by alleviating oxidative stress. GreenMedInfo

PMID:  Int J Mol Sci. 2017 Sep 15 ;18(9). Epub 2017 Sep 15. PMID: 28914791 Abstract Title:  Quercetin Attenuates Manganese-Induced Neuroinflammation by Alleviating Oxidative Stress through Regulation of Apoptosis, iNOS/NF-B and HO-1/Nrf2 Pathways. Abstract:  Manganese (Mn) is an essential trace element required for the development of human body and acts as an enzyme co-factor or activator for various reactions of metabolism. While essential in trace amounts, excessive Mn exposure can result in toxic accumulations in human brain tissue and resulting extrapyramidal symptoms called manganism similar to idiopathic Parkinson's disease (PD). Quercetin (QCT) has been demonstrated to play an important role in altering the progression of neurodegenerative diseases by protecting against oxidative stress. This study aimed to investigate the protective effect of QCT on Mn-induced neurotoxicity and the underlying mechanism in SK-N-MC human neuroblastoma cell line and Sprague-Dawley (SD) male rat brain. The results showed that Mn treatment significantly decreased the cell viability of SK-N-MC cell and increased the release of lactate dehydrogenase (LDH), which was attenuated by QCT pretreatment at 10 and 20g/mL. Compared to the Mn alone group, QCT pretreatment significantly attenuated Mn-induced oxidative stress, mitochondrial dysfunction and apoptosis. Meanwhile, QCT pretreatment markedly downregulated the NF-B but upregulated the heme oxygenase-1 (HO-1) and Nrf2 proteins, compared to the Mn alone group. Our result showed the beneficial effect of QCT on hematological parameters against Mn in rat brain. QCT decrease reactive oxygen species (ROS) and protein carbonyl levels and increased Cu/Zn-superoxide dismutase (SOD) activity induced in Mn-treated rats. QCT administration caused a significant reduction in the Mn-induced neuroinflammation by inhibiting the expression of inflammatory markers such as tumor necrosis factor- (TNF-), interleukin-1 (IL-1), interleukin-6 (IL-6) cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). QCT lowered the Mn elevated levels ofvarious downstream apoptotic markers, including Bax, cytochrome c, cleaved caspase-3 and polymerase-1 (PARP-1), while QCT treatment upregulated anti-apoptotic Bcl-2 proteins and prevented Mn-induced neurodegeneration. Furthermore, administration of QCT (25 and 50 mg/kg) to Mn-exposed rats showed improvement of histopathological alteration in comparison to Mn-treated rats. Moreover, administration of QCT to Mn-exposed rats showed significant reduction of 8-hydroxy-2'-deoxyguanosine (8-OHdG), Bax, activated caspase-3 and PARP-1 immunoreactivity. These results indicate that QCT could effectivelyinhibit Mn induced apoptosis and inflammatory response in SK-N-MC cells and SD rats, which may involve the activation of...

11:40

Quercetin has a protective role of against manganese-induced injury in the liver, kidney, and lungs. GreenMedInfo

PMID:  Drug Des Devel Ther. 2017 ;11:2605-2619. Epub 2017 Sep 5. PMID: 28919711 Abstract Title:  Protective role of quercetin against manganese-induced injury in the liver, kidney, and lung; and hematological parameters in acute and subchronic rat models. Abstract:  Manganese (Mn) is an important mineral element required in trace amounts for development of the human body, while over- or chronic-exposure can cause serious organ toxicity. The current study was designed to evaluate the protective role of quercetin (Qct) against Mn-induced toxicity in the liver, kidney, lung, and hematological parameters in acute and subchronic rat models. Male Sprague Dawley rats were divided into control, Mn (100 mg/kg for acute model and 15 mg/kg for subchronic model), and Mn + Qct (25 and 50 mg/kg) groups in both acute and subchronic models. Our result revealed that Mn + Qct groups effectively reduced Mn-induced ALT, AST, and creatinine levels. However, Mn + Qct groups had effectively reversed Mn-induced alteration of complete blood count, including red blood cells, hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, platelets, and white blood cells. Meanwhile, the Mn + Qct groups had significantly decreased neutrophil and eosinophil and increased lymphocyte levels relative to the Mn group. Additionally, Mn + Qct groups showed a beneficial effect against Mn-induced macrophages and neutrophils. Our result demonstrated that Mn + Qct groups exhibited protective effects on Mn-induced alteration of GRP78, CHOP, and caspase-3 activities. Furthermore, histopathological observation showed that Mn + Qct groups effectively counteracted Mn-induced morphological change in the liver, kidney, and lung. Moreover, immunohistochemically Mn + Qct groups had significantly attenuated Mn-induced 8-oxo-2'-deoxyguanosine immunoreactivity. Our study suggests that Qct could be a substantially promising organ-protective agent against toxic Mn effects and perhaps against other toxic metal chemicals or drugs.

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11:13

Rutin may represent a potential therapeutic agent for diabetic cardiomyopathy. GreenMedInfo

PMID:  Eur J Pharmacol. 2017 Aug 19. Epub 2017 Aug 19. PMID: 28826911 Abstract Title:  Rutin alleviates diabetic cardiomyopathy and improves cardiac function in diabetic ApoEknockout mice. Abstract:  Rutin, a natural bioflavonoid, has demonstrated anti-diabetic and anti-oxidative bioactivity. Oxidative stress is a potential therapeutic target for diabetic cardiomyopathy. We investigated whether rutinadministration (60mg/kg body weight) reduces diabetic cardiomyopathy in a diabetic ApoE knock out mouse model. Diabetes was induced in ApoEknockout mice (male, C57BL/6 background) with a high fat diet combined with injection of streptozotocin. Cardiac function was evaluated by echocardiography and cardiac catheter hemodynamic analysis. Cardiac myocardial hypertrophy, myocardial fibrosis, lipid content, myocardial capillary density, and oxidative stress were detected by a series of histopathological analyses, western blotting, and reactive oxygen species analysis. Diabetic mice showed myocardial hypertrophy, lipid accumulation, myocardial fibrosis, elevated collagen content, deteriorating oxidative stress, and left ventricular systolic and diastolic dysfunction. Rutin reversed the myocardial hypertrophy, alleviated extracellular collagen deposition, and lipid accumulation, but increased capillary density in diabetic myocardial tissues. Moreover, rutin substantially improved cardiac function while decreasing blood glucose and lipid content. Therapeutic rutin administration reduced cardiac remodeling and improved myocardial function in diabetic mice, at least in part by reducing oxidative damage and ectopic lipid deposition, inhibiting fibrosis, and promoting angiogenesis. Thus, rutin may represent a potential therapeutic agent for diabetic cardiomyopathy.

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11:09

Buckeye Arizona Police Take Down Autistic Teen for Stimming AGE OF AUTISM

NOTE: We hope this poor young man is OK. Autism has many variations, versions and vagaries. The epidemic denialists and neurodiversity whitewashers would have you believe autism is simply a Swiss army knife of unique skills for life and not...

11:03

Study: Lauric Acid from Coconut Oil Inhibits Cancer Cell Growth Without Affecting Healthy Cells Health Impact News

Organic coconut oil in the glass jar. Fresh coconut cut in half and leaf for decoration

Comments by Brian Shilhavy
Editor, Health Impact News

A study published this month (September 2017) by researchers from the Department of Pharmacy, Health and Nutritional Sciences, at the University of Calabria in Rende, Italy, and from the Department of Health Sciences at the University Magna Graecia in Catanzaro, Italy, looked at the anti-cancer activity of lauric acid, the main fatty acid found in coconut oil.

While coconut oil continues to get slandered in the U.S. by those with close ties to the pharmaceutical industry, research mainly outside the U.S. continues to show how healthy coconut oil can be, dispelling the common saturated-fat-is-bad myth still being promoted in the U.S.

The study title is: The lauric acid-activated signaling prompts apoptosis in cancer cells, and it was published in the journal Cell Death Recovery.

The study looked at the effects of lauric acid in both breast cancer and colon cancer:

The saturated medium-chain fatty-acid lauric acid (LA) has been associated to certain health-promoting benefits of coconut oil intake, including the improvement of the quality of life in breast cancer patients during chemotherapy.

As it concerns the potential to hamper tumor growth, LA was shown to elicit inhibitory effects only in colon cancer cells. Here, we provide novel insights regarding the molecular mechanisms through which LA triggers antiproliferative and pro-apoptotic effects in both breast and endometrial cancer cells.

Coconut oil is natures richest source of lauric acid, by far, comprising almost 50% of the fatty acids in coconut oil. Human breast milk comes in a distant second at around 6% lauric acid.

Lauric acid has a rich and long history of fighting pathogens, and has been a popular food preservative for many decades. Find out more about peer-reviewed research on lauric acid on our Research Page at CoconutOil.com.

Perhaps the most significant observation documented in this study was the ability...

10:52

Rutin has a protective effect against brain injury induced by acrylamide or gamma radiation. GreenMedInfo

PMID:  Arch Physiol Biochem. 2017 Sep 14:1-9. Epub 2017 Sep 14. PMID: 28906145 Abstract Title:  Protective effect of rutin against brain injury induced by acrylamide or gamma radiation: role of PI3K/AKT/GSK-3/NRF-2 signalling pathway. Abstract:  This study was designed to evaluate the effect of rutin on PI3K/AKT-signalling in case of acrylamide or-radiation-induced neurotoxicity. To induce brain damage, animals were received acrylamide (25mg/kg b.wt./orally/day) or 5Gy of -radiation exposure accompanied with an administration of rutin (200mg/kg b.wt./orally/day). Our data revealed that, compared to acrylamide or -radiation, rutin activated PI3K/AKT/GSK-3/NRF-2-pathway through increased protein levels of p-PI3K, p-AKT and p-GSK-3 and up-regulated the expression of NRF-2. This was achieved by modulating MDA, GST, IL-1, IL-6 and reduced the interference of ROS with IGF-1 and NGF stimulating the PI3K/AKT-signaling. Furthermore, histopathological examinations of brain tissues showed that rutin has modulated tissue architecture after acrylamide or -radiation induced tissue damage. It could be concluded that rutin provides protection effect against acrylamide or -radiation-induced neurotoxicity via activation ofthe PI3K/AKT/GSK-3/NRF-2-pathway by altering the phosphorylation state through its ability to scavenge free radicals generation, modulating gene expression and its anti-inflammatory effects.

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10:32

Low Lymphocyte Count (Lymphocytopenia) What Does It Mean? Healthy and Natural World

Low lymphocyte count (Lymphocytopenia) could indicate that you are at greater risk of developing infections because your lymphocytes (a type of white blood cell) are low. Lymphocytes are a type of white blood cell and they are essential to kill off bacteria and viruses and prevent infections from getting worse. A weakened immune system is often caused by a low number of lymphocytes and other types of white blood cells.

There are 3 types of Lymphocytes in your blood: B lymphocytes (B-cells), T lymphocytes (T-cells), and natural killer cells (NK cells). Together they help to keep you healthy and free of infection. The normal lymphocyte count range is between 1000 and 4800 per microliter of blood and it will take up about 20% to 40% of your total white blood cell count.26

A low level of lymphocytes in the blood can be caused by various factors. For example, nutrient deficiencies, stress, and fasting can all cause your lymphocyte count to drop. If blood tests show a significant drop in the number of lymphocytes then doctors will check for certain diseases like viral infections, autoimmune and inflammatory conditions, or certain cancers.

In many cases, enjoying a healthy diet with plenty of protein, vitamins, and minerals, getting enough rest, and addressing any nutrient deficiencies can help keep your lymphocyte levels normal. However, if doctors suspect a more serious cause of decreased levels of lymphocytes, you will have to treat the underlying medical conditions to get your lymphocyte levels back to normal.

Lymphocytes and What They Do

Lymphocytes are a type of white blood cells and they play an important role in your immune system and are necessary to destroy viruses and bacteria. According to information published by PubMed Health, the three types of lymphocytes B-cells, T-cells, and NK cells (natural killer cells) destroy toxins, bacteria, and viruses. The T cells destroy the bodys own cells that have themselves been taken over by viruses or become cancerous.1

What is Normal Lymphocytes Range?

In order to check for low lymphocytes in a blood test, doctors will perform a differential blood test to count the number of lymphocytes. According to PubMed Health, the normal lymphocyte range in a blood test for adults is between 1000 and 4800/L (or microliters). In children under 2 years old, the range will be significantly higher.2

If your lymphocyte count is less than 1000/L then you have lymphocytopenia (low lymphocyte count). Expert in hematology, Dr. Mary Territo says that lymphocytopenia can only be found by using differential blood test results that count the number of T-cells and B-cells. In some cases, total white blood count can seem normal even when there is a low lymphocyte count.3

What does Low Ly...

10:29

These findings suggest the promising role of mulberry polyphenols for type II diabetics. GreenMedInfo

PMID:  Food Res Int. 2017 Oct ;100(Pt 1):873-884. Epub 2017 Jul 2. PMID: 28873762 Abstract Title:  The novel contributors of anti-diabetic potential in mulberry polyphenols revealed by UHPLC-HR-ESI-TOF-MS/MS. Abstract:  To explore the comprehensive phenolic profile of mulberry (Morus alba L.) fruit and reveal the novel anti-diabetic constituents, mulberry polyphenols (MP) were fractionated through gradient ethanol elution and subjected to composition and bioactivity analysis. Forty-seven phenolic compounds were identified and quantified through UHPLC-HR-ESI-TOF-MS/MS, including twenty-one newly identified compounds such as delphinidin 3-rutinoside-5-glucoside and cyanidin 3-rutinoside dimer. The antioxidant activity and anti-diabetic potential of fractionated MP were analyzed in vitro and ex vivo with HepG2 and pancreatic-cell RIN-m5F. Hierarchical cluster analysis and Pearson correlation coefficients revealed compounds such as syringic acid and galloylcyanidin-glycoside contributed most to inhibit -glucosidase activity. Quercetin and cyanidin-glycosides were essential for cellular antioxidant activity. Dihydroquercetin and 1,5-dicaffeoylquinic acid were newly identified and validated as the main contributors after rutin to protect RIN-m5F cells against glucotoxicity. Such findings suggest the promising role of MP for type II diabetics and lay the foundation of further utilization and investigation.

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09:58

The current research verified that oregano and its main constituents could be potentially utilized as anticancer therapeutic agents. GreenMedInfo

PMID:  Molecules. 2017 Aug 30 ;22(9). Epub 2017 Aug 30. PMID: 28867805 Abstract Title:  Cytotoxic Activity of Origanum Vulgare L. on Hepatocellular Carcinoma cell Line HepG2 and Evaluation of its Biological Activity. Abstract:  The potential of plant essential oils (EOs) in anticancer treatment has recently received many research efforts to overcome the development of multidrug resistance and their negative side effects. The aims of the current research are to study (i) the cytotoxic effect of the crude EO extracted from Origanum vulgare subsp hirtum and its main constituents (carvacrol, thymol, citral and limonene) on hepatocarcinoma HepG2 and healthy human renal cells HEK293; (ii) the antibacterial and phytotoxic activities of the above EO and its main constituents. Results showed that cell viability percentage of treated HepG2 by EO and its main constituents was significantly decreased when compared to untreated cells. The calculated inhibition concentration (IC50) values for HepG2 were lower than healthy renal cells, indicating the sort of selectivity of the studied substances. Citral is not potentially recommended as an anticancer therapeutic agent, since there are no significant differences between IC50 values against both tested cell lines. Results showed also that oregano EO and its main constituents have a significant antibacterial activity and a moderate phytotoxic effect. The current research verified that oregano EO and its main constituents could be potentially utilized as anticancer therapeutic agents.

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09:36

Caffeic acid phenethyl ester is protective in experimental ulcerative colitis GreenMedInfo

PMID:  Inflammopharmacology. 2017 May 20. Epub 2017 May 20. PMID: 28528363 Abstract Title:  Caffeic acid phenethyl ester is protective in experimental ulcerative colitis via reduction in levels of pro-inflammatory mediators and enhancement of epithelial barrier function. Abstract:  BACKGROUND: Inhibition of the nuclear factor kappa beta (NF-) pathway has been proposed as a therapeutic target due to its key role in the expression of pro-inflammatory genes, including pro-inflammatory cytokines, chemokines, and adhesion molecules. Caffeic acid phenethyl ester (CAPE) is a naturally occurring anti-inflammatory agent, found in propolis,and has been reported as a specific inhibitor of NF-. However, the impact of CAPE on levels of myeloperoxidases (MPO) and pro-inflammatory cytokines during inflammation is not clear. The aims of this study were to investigate the protective efficacy of CAPE in the mouse model of colitis and determine its effect on MPO activity, pro-inflammatory cytokines levels, and intestinal permeability.METHOD: Dextran sulphate sodium was administered in drinking water to induce colitis in C57/BL6 mice before treatment with intraperitoneal administration of CAPE (30 mg kg(-1) day(-1)). Disease activity index (DAI) score, colon length and tissue histology levels of MPO, pro-inflammatory cytokines, and intestinal permeability were observed.RESULTS: CAPE-treated mice had lower DAI and tissue inflammation scores, with improved epithelial barrier protection and significant reduction in the level of MPO and pro-inflammatory cytokines.CONCLUSION: Our results show that CAPE is effective in suppressing inflammation-triggered MPO activity and pro-inflammatory cytokines production while enhancing epithelial barrier function in experimental colitis. Thus, we conclude that CAPE could be a potential therapeutic agent for further clinical investigations for treatment of inflammatory bowel diseases in humans.

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09:33

What Is Spotting and What Does Spotting Look Like? Healthy and Natural World

Spotting is light bleeding that can look like the start of your regular menstrual period but happens before or after your period. Although you may be worried about light vaginal bleeding between your monthly periods, there usually isnt anything to worry about. Spotting looks like small dark brown spots or light pink marks on your underwear which makes it possible to tell apart from regular menstrual bleeding.

Some occasional light spotting between your periods is viewed as normal and can be caused by stress, using birth control, or even a sign that ovulation has occurred. In fact, implantation spotting before your period is due could be a sign that you are pregnant. However, there are some conditions where vaginal spotting when you dont have your period can be a cause for concern. Uterine fibroids, ovarian cysts, infections, and cancer can cause light to heavy vaginal bleeding and may be associated with abdominal pain, fever, and pain during bowel movements. Some spotting can occur during pregnancy and you should always speak to your doctor or obstetrician about the bleeding.

In this article, you will learn about what spotting looks like and how to tell the difference between period bleeding and spotting. You will also find out when spotting is considered normal and when you should speak to your doctor about abnormal vaginal bleeding.

What is Spotting?

Spotting is referred to by doctors as abnormal vaginal bleeding. According to staff from the Mayo Clinic, spotting is when you notice small amounts of blood when you are not expecting your period. The spots of blood are often seen after wiping when you have used the bathroom or you may notice them on your underwear.1

According to Dr. William Blahd on WebMD, light spotting has many causes and doesnt necessarily mean that you have a serious condition. For example, Dr. Blahd says that some light bleeding can happen with ovulation and even in pregnancy, and some minimal spotting can be considered normal.2

Spotting vs. Period How to Tell the Difference

Knowing what spotting looks like and when it happens can help you tell the difference between regular menstrual flow and spotting. For some women, spotting can be the first sign that their menstrual period has started. So, telling spotting apart from regular menstrual bleeding requires that you observe and know what is normal with your monthly cycle.

What is considered a light period?

Having your period marks the start of your regular menstrual cycle. According to Dr. Traci Johnson on WebMD, what is considered normal depends on each woman and their menstrual cycle. In general, a light period is one where bleeding lasts a short time and the blood flow is relatively light. For example, some women have very light periods that only last 2-3 days with light blood flow.3 Light blood flow might be as little as 10 ml, or 2...

09:14

Intrathecal CAPE administration following SCI decreases tissue and serum IL-6 levels as well as decreases spinal cord edema and microhemorrage. GreenMedInfo

PMID:  Turk Neurosurg. 2017 Apr 27. Epub 2017 Apr 27. PMID: 28585671 Abstract Title:  Effects of Intrathecal Caffeic Acid Phenethyl Ester (CAPE) on IL-6 and TNF- Levels and Local Inflammatory Responses in Spinal Cord Injuries. Abstract:  AIM: To investigate the effects of intrathecal caffeic acid phenethyl ester (CAPE) on tissue and serum IL-6 and TNF- levels following spinal cord injury (SCI) as well as its effects on edema and microhemorrage.MATERIAL AND METHODS: Forty rats were divided into four groups. The sham group underwent single-level laminectomy and then received an intrathecal injection of isotonic saline. The control group received an intrathecal injection of isotonic saline following SCI induction. The methylprednisolone (MP) group received a single dose of MP intrathecally following SCI. The CAPE group received a single dose of CAPE intrathecally following SCI. IL-6 and TNF- levels were determined using the ELISA method. Spinal cord samples were evaluated histopathologically.RESULTS: The decrease in IL-6 levels in the CAPE group was significantly higher than that in the sham and control groups. However, this decrease wasn't as significant as that in the MP group. No significant decrease was identified in TNF- levels. A significant decrease was observed in spinal cord edema and microhemorrage in the CAPE group. A decrease in edema was observed in the MP group, but no effect was observed on microhemorrage.CONCLUSION: Intrathecal CAPE administration following SCI decreases tissue and serum IL-6 levels as well as decreases spinal cord edema and microhemorrage.

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09:06

Cinnamaldehyde supplementation is shown to improve glucose and lipid homeostasis in diabetic animals. GreenMedInfo

PMID:  Pharmacol Res. 2017 Aug ;122:78-89. Epub 2017 May 27. PMID: 28559210 Abstract Title:  Cinnamaldehyde in diabetes: A review of pharmacology, pharmacokinetics and safety. Abstract:  Cinnamaldehyde, one of the active components derived from Cinnamon, has been used as a natural flavorant and fragrance agent in kitchen and industry. Emerging studies have been performed over the past decades to evaluate its beneficial role in management of diabetes and its complications. This review highlights recent advances of cinnamaldehyde in its glucolipid lowering effects, its pharmacokinetics, and its safety by consulting the Pubmed, China Knowledge Resource Integrated, China Science and Technology Journal, National Science and Technology Library, Wanfang Data, and the Web of Science Databases. For the inquiries, keywords such as Cinnamon, cinnamaldehyde, property, synthesis, diabetes, obesity, pharmacokinetics, and safety were used in various combinations. Accumulating evidence supports the notion that cinnamaldehyde exhibits glucolipid lowering effects in diabetic animals by increasing glucose uptake and improving insulin sensitivity in adipose and skeletal muscle tissues, improving glycogen synthesis in liver, restoring pancreatic islets dysfunction, slowing gastric emptying rates, and improving diabetic renal and brain disorders. Cinnamaldehyde exerts these effects through its action on multiple signaling pathways, including PPARs, AMPK, PI3K/IRS-1, RBP4-GLUT4, and ERK/JNK/p38MAPK, TRPA1-ghrelin and Nrf2 pathways. In addition, cinnamaldehyde seems to regulate the activities of PTP1B and-amylase. Furthermore, cinnamaldehyde has the potential of metalizing into cinnamyl alcohol and methyl cinnamate and cinnamic acid in the body. Finally, there is a potential toxicity concern about this compound. In summary, cinnamaldehyde supplementation is shown to improve glucose and lipid homeostasis in diabetic animals, which may provide a new option for diabetic intervention. To this end, further scientific evidences are required from clinical trials on its glucose regulating effects and safety.

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09:01

Dietary cinnamaldehyde enhances acquisition of specific antibodies following helminth infection in pigs. GreenMedInfo

PMID:  Vet Immunol Immunopathol. 2017 Jul ;189:43-52. Epub 2017 Jun 17. PMID: 28669386 Abstract Title:  Dietary cinnamaldehyde enhances acquisition of specific antibodies following helminth infection in pigs. Abstract:  Dietary phytonutrients such as cinnamaldehyde (CA) may contribute to immune function during pathogen infections, and CA has been reported to have positive effects on gut health when used as feed additive for livestock. Here, we investigated whether CA could enhance antibody production and specific immune responses during infection with an enteric pathogen. We examined the effect of dietary CA on plasma antibody levels in parasite-nave pigs, and subsequently acquisition of humoral immune responses during infection with the parasitic nematode Ascaris suum. Parasite-nave pigs fed diets supplemented with CA had higher levels of total IgA and IgG in plasma, and A. suum-infected pigs fed CA had higher levels of parasite-specificIgM and IgA in plasma 14days post-infection. Moreover, dietary CA increased expression of genes encoding the B-cell marker CD19, sodium/glucose co-transporter1 (SCA5L1) and glucose transporter 2 (SLC2A2) in the jejunal mucosa of A.suum-infected pigs. Dietary CA induced only limited changes in the composition of the prokaryotic gut microbiota of A. suum-infected pigs, and in vitro experiments showed that CA did not directly induce proliferation or increase secretion of IgG and IgA from lymphocytes. Our results demonstrate that dietary CA can significantly enhance acquisition of specific immuneresponses in pigs. The underlying mechanism remains obscure, but apparently does not derive simply from direct contact between CA and host lymphocytes and appears to be independent of the gut microbiota.

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08:54

Cinnamaldehyde exhibits therapeutic potency against obesity by inducing the browning of white adipose tissue. GreenMedInfo

PMID:  Cell Physiol Biochem. 2017 Jul 18 ;42(4):1514-1525. Epub 2017 Jul 18. PMID: 28719892 Abstract Title:  Cinnamaldehyde Ameliorates Diet-Induced Obesity in Mice by Inducing Browning of White Adipose Tissue. Abstract:  BACKGROUND/AIMS: Obesity has become a major health concern with few effective medications. Cinnamaldehyde (CA) has been reported to exhibit anti-diabetic and anti-inflammatory properties. However, whether CA shows anti-obesity activity remains unknown. Therefore, the present study aimed to investigate the potential anti-obesity effects of CA on mice fed a high-fat diet (HFD) and to explore the possible mechanisms involved.METHODS: Male C57BL/6J mice fed an HFD for 12 weeks were supplemented with CA (40 mg/kg/day) via gavage for an additional 8 weeks. Mice fed a standard diet were used as normal controls.RESULTS: The results revealed that CA treatment decreased body weight, fat mass, food intake, and serum lipid, free fatty acid and leptin levels. CA administration also improved insulin sensitivity in HFD-induced obese mice. Additionally, CA inhibited the hypertrophy of adipose tissue and induced browning of white adipose tissue. Uncoupling protein 1 (UCP1) was expressed in white adipose tissue after the oral administration of CA. Furthermore, CA enhanced the expression of the peroxisome proliferator-activated receptor (PPAR), PR domain-containing 16 (PRDM16) and PPAR coactivator 1 (PGC-1) proteins in both brown and white adipose tissues.CONCLUSIONS: The results suggest that CA exhibits therapeutic potency against obesity by inducing the browning of white adipose tissue in HFD-fed mice.

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08:47

Eucalyptol, sabinene and cinnamaldehyde could be potent inhibitors of salmonella target protein L-asparaginase. GreenMedInfo

PMID:  3 Biotech. 2017 Aug ;7(4):258. Epub 2017 Jul 22. PMID: 28735432 Abstract Title:  Eucalyptol, sabinene and cinnamaldehyde: potent inhibitors of salmonella target protein L-asparaginase. Abstract:  Salmonella typhimurium is a severe threat to human life. The treatment became more difficult with the emergence of multidrug resistance. In the present in silico study, a novel drug target L-asparaginase was tested against three ligands eucalyptol, sabinene, and cinnamaldehyde, major components of cardamom, nutmeg, and cinnamon, respectively. The lowest docking score was obtained for sabinene followed by eucalyptol and cinnamaldehyde i.e. -5.648, -3.939 and -3.469. The docking score of sabinene is also better than the standard drug, Ciprofloxacin (-4.661) and natural substrate L-asparagine (-5.497). The amino acid residues involved in interactions inside the binding pocket are threonine 115 and threonine 35. The ADMET profile studied, also suggests the potency of the test ligands as a drug candidate. The results suggest they could be safe alternatives of chemical compounds to treat infections and combat multidrug-resistant bacteria.

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08:37

Cinnamaldehyde has a protective effect in the endotoxin poisoned mice through the inhibition of NLRP3 inflammasome activation. GreenMedInfo

PMID:  Immunopharmacol Immunotoxicol. 2017 Oct ;39(5):296-304. Epub 2017 Aug 1. PMID: 28762847 Abstract Title:  Inhibition of NLRP3 inflammasome: a new protective mechanism of cinnamaldehyde in endotoxin poisoning of mice. Abstract:  CONTEXT: Cinnamaldehyde (CA) has a protective effect in endotoxin poisoning of mice, but there is no direct evidence for the protective effect of CA through inhibition of NLRP3 inflammasome activation in endotoxin poisoning of mice.OBJECTIVE: We aimed to investigate the protective mechanism of CA in endotoxin poisoned mice through NLRP3 inflammasome.MATERIALS AND METHODS: First, we evaluated the anti-inflammatory effect of CA in phorbol-12-myristate acetate-differentiated THP-1 cells through the NLRP3 inflammasome. Second, in a mouse model of lipopolysaccharide (LPS)-induced endotoxin poisoning, CA was administrated for 5 d (once a day) before the 15mg/kg LPS challenge. Then, the levels of IL-1 in serum were measured, and the effect of CA on the NLRP3 inflammasome activation and the expression of cathepsin B and P2X7R proteins in lung were explored.RESULTS: In vitro, CA decreased the levels of p20, pro-IL-1 and IL-1 in cell culture supernatants, as well as the expression of NLRP3 and IL-1 mRNA in cells. In vivo, CA decreased IL-1 production in serum. Furthermore, CA suppressed LPS-induced NLRP3, p20, Pro-IL-1, P2X7 receptor (P2X7R) and cathepsin B protein expression in lung, as well as the expression of NLRP3 and IL-1 mRNA.CONCLUSIONS: CA has a protective effect in the endotoxin poisoned mice through the inhibition of NLRP3 inflammasome activation. Furthermore, CA suppresses the NLRP3 inflammasome activation by inhibiting the expression of cathepsin B and P2X7R protein expression. CA can be considered as a potential therapeutic candidate for diseases involved in endotoxin poisoning such as sepsis.

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08:29

Studies Link Heavy Metals to the Explosion of Neurodevelopmental Disorders and Declining IQ in American Children Vaccine Impact

No-KN-and-V-Graphic_PuzzleBrain02

by Robert F. Kennedy, Jr.
World Mercury Project

A silent pandemic of neurodevelopmental toxicity is disabling a generation of children around the world. This is the verdict of neurology experts Philippe Grandjean and Philip Landrigan in a 2014 report in Lancet Neurology. The staggering tsunami of developmental disabilities now affects at least one in six children in the U.S. and millions more worldwide. Two new studies suggest that the most common of these illnessesautism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD) and ticsare related to each other and may share common causation. The culprit? Environmental toxins, particularly heavy metals.

About 11% (or one in nine 4-17-year-olds) have received an ADHD diagnosisand in some states, as many as 19%. The most recent ASD estimates in the U.S., from 2014 data, report a prevalence of one in 45 children, representing a significant increase compared to 20112013.

08:26

Cinnamaldehyde is a potential therapeutic agent for cell protection against oxidative stress. GreenMedInfo

PMID:  Eur J Pharmacol. 2017 Sep 4. Epub 2017 Sep 4. PMID: 28882558 Abstract Title:  Cinnamaldehyde protects human dental pulp cells against oxidative stress through the Nrf2/HO-1-dependent antioxidant response. Abstract:  Cinnamaldehyde (CA) has various functional properties, such as anti-cancer, anti-microbial, anti-inflammatory, and anti-oxidant activities. This study examined the intracellular signaling mechanisms of CA on the oxidative stress response in human dental pulp cells (hDPCs). The results showed that CA did not have any cell cytotoxicity or cause morphological changes at concentrations up to 50M. A CA treatment strongly up-regulated the cellular protein level of heme oxygenase-1 (HO-1) and promoted Nrf2 translocation to the nucleus. CA-mediated Nrf2/HO-1 activation reduced the level of reactive oxygen species and protected the hDPCs from H2O2-induced oxidative stress, which induces apoptosis. Moreover, HO-1 depletion by siRNA attenuated the CA-mediated cell protection against oxidative stress. These results indicate that CA protects hDPCs dysfunction under oxidative stress conditions, and this effect is mediated by Nrf2 activation and the up-regulation of HO-1. Overall, these observations suggest that CA is a potential therapeutic agent for cell protection against oxidative stress.

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08:14

Pollution soars in Houston after chemical industry leaks Health Nut News

Houston is still suffering from Hurricane Harvey, long after the storm has passed. But not just because of the flooding or number of damaged homes and roads. Rather, its because of the leeching of thousands of tons of pollutants thanks to their large petrochemical industry. RELATED ARTICLE: ExxonMobil refineries damaged in Hurricane Harvey and releasing hazardous pollutants The

08:11

Petroleum Jelly new research findings two


Stop Using Vaseline Immediately! 4 reasons you should never put petroleum jelly on your skin

Petroleum Jelly, the main ingredient in Vaseline, is often used in beauty products and even on its own to moisturize skin. Its cheap. Its unscented. It seems to work well for softening skin, so what could be the problem?

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MOAB 46913, Navigation Neutral, Markup Window, ProductView Box_2, Size (w:336, h:280), CrossOvers True, ColSpan 1, RowSpan 1 


What is Petroleum Jelly?
Petroleum jelly is a byproduct of the oil refining process. This means it is not sustainable or eco-friendly, and it also explains some of the potential problems with using it.
Petroleum jelly&nb...

08:06

These finding suggests that Cinnamaldehyde is a potential anti-inflammatory agent in treatment the acute lung injury. GreenMedInfo

PMID:  Cell Mol Biol (Noisy-le-grand). 2017 Aug 30 ;63(8):58-63. Epub 2017 Aug 30. PMID: 28886315 Abstract Title:  The protective effect of cinnamaldehyde on lipopolysaccharide induced acute lung injury in mice. Abstract:  The study wasintended to examinethe protective effect of cinnamaldehyde (CM) on lipopolysaccharide (LPS)-induced acute lung injury (ALI) mice model.The results of the investigation confirmed that, LPS induced inflammatory cytokines such as TNF-, IL-6, IL-13 and IL-1 were significantly decreased by CM. CM also up-regulated level of IL-10. We found that CM significantly attenuated LPS-induced TLR4 expression, NF-B activation and MPO activity in the lung tissues. It markedly reduced lung wet/dry ratio, and improved typical and severe pathological changes including pulmonary edema in the LPS induced ALI mice. Moreover, CM significantly inhibited neutrophils, macrophages and total cell number in the bronchoalveolar lavage fluid (BALF). In our study, we noted that TLR4-NF-B signaling pathway was involved in acute lung injury.The results revealed the protective effects of CM in LPS-induced ALI, through suppressionTLR4-NF-B signaling pathway. Our finding suggests that Cinnamaldehyde is a potential anti-inflammatory agent in treatment the acute lung injury.

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08:00

Serum Ferritin and GGT Two Potent Health Indicators You Need to Know new research findings two

Serum Ferritin and GGT Two Potent Health Indicators You Need to Know

  • 912 


Story at-a-glance
  • By monitoring your serum ferritin (stored iron) and GGT levels and taking steps to lower them if theyre too high, you can avoid serious health problems
  • Virtually all adult men and postmenopausal women are at risk for iron overload due to inefficient iron excretion. Left untreated, it can contribute to cancer, heart disease, neurodegenerative diseases and other chronic health problems
  • GGT is a liver enzyme involved in glutathione metabolism and the transport of amino acids. GGT can be used as a screening marker for excess free iron and is a potent predictor of mortality


By Dr. Mercola
While many health screens and lab tests are overrated or unnecessary, there are a few that are vitally important, such as vitamin D. I recommend checking your vitamin D level at least twice a year.
Two other really important tests are serum ferritin (which measures stored iron) and gamma-glutamyl transpeptidase or sometimes called gamma-glutamyltransferase (GGT; a liver enzyme correlated with iron toxicity, disease risk and all-cause mortality). By monitoring your serum ferritin and GGT levels and taking steps to lower them if they're too high, y...

07:57

These results indicate cinnamaldehyde has a potential protective effect against glutamate-induced oxidative stress and apoptosis in PC12 cells. GreenMedInfo

PMID:  Eur J Pharmacol. 2017 Sep 9. Epub 2017 Sep 9. PMID: 28893578 Abstract Title:  Protective effect of cinnamaldehyde against glutamate-induced oxidative stress and apoptosis in PC12 cells. Abstract:  Cinnamaldehyde is a main ingredient of cinnamon oils from the stem bark of Cinnamomum cassia, which has been widely used in food and traditional herbal medicine in Asia. In the present study, the neuroprotective effects and the potential mechanisms of cinnamaldehyde against glutamate-induced oxidative stress in PC12 cells were investigated. Exposure to 4mM glutamate altered the GSH, MDA levels and SOD activity, caused the generation of reactive oxygen species, resulted in the induction of oxidative stress in PC12 cell, ultimately induced cell death. However, pretreatment with cinnamaldehyde at 5, 10 and 20M significantly attenuated cell viability loss, reduced the generation of reactive oxygen species, stabilised mitochondrial membrane potential (MMP), decreased the release of cytochrome c and limited the activities of caspase-9 and -3. In addition, cinnamaldehyde also markedly increased Bcl-2 while inhibiting Bax expressionand decreased the LC3-II/LC3-I ratio. These results indicate that cinnamaldehyde exists a potential protective effect against glutamate-induced oxidative stress and apoptosis in PC12 cells.

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07:50

Encapsulated cinnamaldehyde had enhanced killing and antibiofilm activity against candida albicans. GreenMedInfo

PMID:  Front Microbiol. 2017 ;8:1641. Epub 2017 Aug 29. PMID: 28900419 Abstract Title:  Enhanced Killing and Antibiofilm Activity of Encapsulated Cinnamaldehyde against Candida albicans. Abstract:  Candida sp. impelled opportunistic infection in immune-compromised patients ensuing from asymptomatic colonization to pathogenic forms. Moreover, slow spread of Candida species inducing refractory mucosal and invasive infections brings acute resistance to antifungal drugs. Hence, here we probed the effect of encapsulated preparation of cinnamaldehyde (CNMA) in multilamellar liposomes (ML) against Candida albicans. The efficacy of ML-CNMA against Candida biofilm was assessed by scanning electron microscopy, transmission electron microscopy, as well as light microscopy and its percent inhibition, was determined by XTT [2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide] and crystal violet assay. ML-CNMA showed more fungicidal activity than free CNMA as well as multilamellar liposomal amphotericin B (ML-Amp B), which was further confirmed by spot test assay and Log-logistic dose-response analysis. Antifungal activity was driven by reactive oxygen species and cellular damage by sustained release of CNMA. Effect on hyphal formation during 48 h in presence/absence of ML-CNMA was observed under a microscope and further substantiated by RT-PCR by amplifying HWP1, the gene responsible for hyphal wall protein formation. Apoptotic programmed cell death was analyzed by FACS analysis which was further confirmed by cytochrome C release assay. This study elucidates the mechanistic insight of the enhanced antifungal activity of ML preparation of CNMA against Candida infections.

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07:22

Big Corps Selling Lower Quality Foods To Poorer East EU Nations Natural Blaze

By Heather CallaghanEditor

A Slovenian and an Australian sip a Coca-Cola at the same time, although worlds apart. The latter enjoys a typical formula. But the formers is exploding with elevated sugar content and fructo-glucose. The Coke in Prague might dance a more muted jig on the taste buds than the one in London. What happened?

People have suspected double standards on the part of Big Food corporations and their goods in different countries for decades now. Turns out, they were on to something.

Vra Jourov, European Commissioner for Justice, Consumers and Gender Equality, stated that multinational food companies are selling vastly different products to different countries, but use identical branding on their packaging.

She says that many foods sold in Eastern Europe by Western multinational corporations are significantly inferior to the same brands product sold in Western Europe.

She voiced the exasperation of the Eastern European people who feel the need to buy things abroad in order to have fish fingers that will contain fish meat, or orange juice that will contain oranges.

The frustration is growing and we should do something against it, she told The Guardian.

However, aside from the Coca-Cola, Sput...

07:21

Half of All Men Cant Answer this Insanely Basic Question About Womens Anatomy, According to Survey Healthy Holistic Living

This article is shared with permission from our friends at IFL Science. A new poll from The Eve Appeal, a cancer research charity, has revealed that 50 percent of men are unable to point to the vagina on a diagram. The survey of 1,000 men came out just before Septembers Gynaecological Cancer Awareness...

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The post Half of All Men Cant Answer this Insanely Basic Question About Womens Anatomy, According to Survey appeared first on Healthy Holistic Living.

07:20

German Doctor Links Nano-aluminum, Glyphosate and Parasites to Chronic Disease Develops Healing Protocol Vaccine Impact

Dr. Dietrich Klinghardt 2

Dr. Dietrich Klinghardt of Sophia Health Institute. Image source.

Nano-Aluminum, Glyphosate, and the Life Saving Work of Parasites

by John P. Thomas
Health Impact News

The bodies of Americans are saturated with very high levels of nano-aluminum. This provides ideal conditions for severe parasite infestation. These burdens are making us a country of chronically ill and cognitively impaired people.

This is part two of a series on nanotechnology and its effect on human health.

In the first article, I provided an overview of the safety concerns associated with manmade nanotechnology, and identified nano-aluminum as a serious threat to our health. The lack of safety studies on most forms of nanotechnology makes it hard to assess and rank the long-term risks posed by the thousands of nanosized ingredients that are being used in food, cosmetics, consumer products, and industry/military applications. However, evidence is pointing to nano-aluminum as being an extremely dangerous nanotechnology.

The sickest people have the highest levels of nano-aluminum and parasites in their bodies, and when they are helped to detox their aluminum and control their parasites, they begin to heal from chronic illness. The presence of nano-aluminum goes hand-in-hand with the presence of parasites. Lets start examining this relationship by looking at nano-aluminum.

The presence of nano-aluminum in our bodies cannot be measured through conventional lab tests. It requires sophisticated electron microscopic examination of samples, which strangely is not available in the United States. A doctor cant just order a nano-aluminum test to check your status, because U.S. labs arent able or arent permitted to do this test.

Please use this link to read the first article in this series:

Nano-Toxicity: Are Nanoparticles in Food and Our Environment the New Health Epidemic?

The Source of Our Nano-Aluminum Exposure

As explained in the...

07:20

These findings demonstrate that CAPE may contribute to the chemopreventive and chemotherapeutic effects of C. cassia. GreenMedInfo

PMID:  J Nat Prod. 2017 Jul 28 ;80(7):2124-2130. Epub 2017 Jul 6. PMID: 28682072 Abstract Title:  Caffeic Acid Phenethyl Ester from the Twigs of Cinnamomum cassia Inhibits Malignant Cell Transformation by Inducing c-Fos Degradation. Abstract:  The twigs of Cinnamomum cassia, commonly referred to as Cinnamomi Ramulus, are widely used as one of the primary ingredients in Chinese/Korean traditional medicines that have anticancer effects. However, the active constituents responsible for its anticancer effects and their molecular mechanisms still remain to be elucidated. Caffeic acid phenethyl ester (CAPE) and caffeic acid (CA) were isolated for the first time from C. cassia using LC-MS-guided phytochemical isolation methods. CAPE significantly suppressed EGF- and TPA-induced cell transformation of JB6 P+ cells at sub-micromolar concentrations, whereas CA, a structurally similar compound to CAPE, had no such effect. The antiproliferative and chemopreventive activity of CAPE was found to arise through the inhibition of AP-1 transcriptional activity via the promotion of c-Fos degradation. These findings demonstrate that CAPE may contribute to the chemopreventive/chemotherapeutic effects of C. cassia through downregulating c-Fos.

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07:13

25 No-Fuss Ways to Drop One Pound a Week Healthy Holistic Living

This article is shared with permission from our friends at Womanista. Cutting out excess calories from your diet is important when trying to lose weight, but its much easier said than done. According to Health Magazine, if you cut 500 calories a day, youll be dropping a pound a week! Check...

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The post 25 No-Fuss Ways to Drop One Pound a Week appeared first on Healthy Holistic Living.

07:07

90% of People Who Die From This Preventable Disease Never Even Knew They Had It Healthy Holistic Living

This article is shared with permission from our friends at NutritionFacts. Diverticula are out-pouchings of our intestine. Doctors like using a tire analogy: high pressures within the gut can force the intestines to balloon out through weak spots in the intestinal wall like an inner tube poking out through a worn...

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The post 90% of People Who Die From This Preventable Disease Never Even Knew They Had It appeared first on Healthy Holistic Living.

07:03

Air Travel Exposes You to Radiation, But What are the Actual Health Risks? Healthy Holistic Living

This article is shared with permission from our friends at IFL Science. This past April, business traveler Tom Stuker became the worlds most frequent flyer, logging 18,000,000 miles of air travel on United Airlines over the last 14 years. Thats a lot of time up in the air. If Stukers traveling behaviors are...

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The post Air Travel Exposes You to Radiation, But What are the Actual Health Risks? appeared first on Healthy Holistic Living.

06:58

CAPE seems to be effective agent and may be related to its potent antioxidant, anti-inflammatory properties and action as an Nrf2 activator. GreenMedInfo

PMID:  Environ Toxicol Pharmacol. 2017 Sep ;54:80-92. Epub 2017 Jun 28. PMID: 28704754 Abstract Title:  Metabolomics study of cadmium-induced diabetic nephropathy and protective effect of caffeic acid phenethyl ester using UPLC-Q-TOF-MS combined with pattern recognition. Abstract:  Diabetic nephropathy (DN) is the most severe complication of diabetes and multiple factors are involved in the pathogenesis of DN. Among them, cadmium (Cd) acts as a risk factor inducing the occurrence of DN. The present study focused on investigating the protective role of caffeic acid phenethyl ester (CAPE), an active component of propolis from honeybee hives, against Cd-induced DN in mice based on ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS)and pattern recognition. Serum and urine biochemical indexes were detected and histopathological observation has been done to evaluate the damage of Cd on animals. Moreover, the global serum profiles of different groups were distinguished by UPLC-Q-TOF-MS and principal component analysis (PCA) were applied for group differentiation and marker selection. Moreover, the influence of Cd on the oxidative status in DN mice were also evaluated by assessing the parameters of oxidative stress, proinflammatory cytokines and antioxidant competence. As shown in the scores plots, the distinct clustering among controls, DN and CAPE groups were observed, significant changes in serum levels of LysoPC(18:1(11Z)), 2,3-dinor-8-iso-PGF2a, PS(18:1(9Z)/18:1(9Z)), DG(17:0/22:4 (7Z,10Z, 13Z, 16Z)/0:0) and Arachidonic acid(AA) were noted and identified as potential biomarkers, the effect of CAPE reverted them back to near normalcy. Further, It was observed a significant improvement in lipid peroxides (LPO) and protein carbonyls (PCO) levels in Cd-induced DN kidneys along with a significant decline in superoxide dismutase (SOD), catalase (CAT), and reduced glutathione (GSH) levels, however, CAPE relieved these changes. In conclusion, the study suggested that the pathogenesis of DN caused by Cd probably owes to the perturbations of lipid metabolism and AA metabolism; CAPE seems to be effective agent and may be related to its potent antioxidant, anti-inflammatory properties and action as an Nrf2 activator.

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06:57

FDA Approves Installation of Reverse Feeding Tubes for People Who Eat Too Much Healthy Holistic Living

This article is shared with permission from our friends at IFL Science. Being morbidly obese is incredibly damaging to your health. For some people though, dieting and exercise are simply not enough. For these people, they may need to go under the knife to either receive bariatric surgery or, as the...

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The post FDA Approves Installation of Reverse Feeding Tubes for People Who Eat Too Much appeared first on Healthy Holistic Living.

06:49

Most Digestive Problems Could Be Solved by Eating These Foods Regularly Healthy Holistic Living

This article is shared with permission from our friends at Doctors Health Press. Disclaimer: Results are not guaranteed*** and may vary from person to person***. Its amazing how much has changed in understanding the inner workings of the human body over the last few years. And with every passing day, there...

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The post Most Digestive Problems Could Be Solved by Eating These Foods Regularly appeared first on Healthy Holistic Living.

06:47

Caffeic acid phenethyl ester can ameliorate on insulin resistance through modulation of JNK and NF-B signalling pathway in mice and HepG2 cells. GreenMedInfo

PMID:  J Agric Food Chem. 2017 Aug 11. Epub 2017 Aug 11. PMID: 28799756 Abstract Title:  Caffeic Acid Phenethyl Ester (Propolis Extract) Ameliorates Insulin Resistance by Inhibiting JNK and NF-B Inflammatory Pathways in Diabetic Mice and HepG2 Cells Models. Abstract:  Caffeic acid phenethyl ester (CAPE), extracted from propolis, was evaluated the ameliorative effects on insulin resistance and identified the mechanisms, using noninsulin-dependent diabetes mellitus (NIDDM) model mice and insulin resistance (IR) model cells. After 5-week of CAPE supplementation, insulin sensitivity, hyperlipidemia, and peroxisome proliferator-activated receptor- (PPAR-) levels were improved in mice. Pro-inflammatory cytokines in serum and the expressions of tumour necrosis factor- alpha (TNF-) mRNA in tissues were markedly down-regulated from CAPE-treated mice. In vitro, CAPE supplement significantly improved glucose consumption, glucose uptake, glycogen content, and oxidative stress and decreased expression of glucose-6-phosphatase (G6Pase) mRNA in cells. Both in vivo and vitro, CAPE enhanced p-Akt (Ser473) and p-insulin receptor substrate (IRS)-1 (Tyr612), but inhibited p-JNK (Thr183/Tyr185), p-NF-B p65 (Ser536) and nuclear translocation ofp-NF-B p65 (Ser536). In summary, CAPE can ameliorate on insulin resistance through modulation of JNK and NF-B signaling pathway in mice and HepG2 cells.

read more

06:44

German Doctor Links Nano-aluminum, Glyphosate and Parasites to Chronic Disease Develops Healing Protocol Health Impact News

Dr. Dietrich Klinghardt 2

Dr. Dietrich Klinghardt of Sophia Health Institute. Image source.

Nano-Aluminum, Glyphosate, and the Life Saving Work of Parasites

by John P. Thomas
Health Impact News

The bodies of Americans are saturated with very high levels of nano-aluminum. This provides ideal conditions for severe parasite infestation. These burdens are making us a country of chronically ill and cognitively impaired people.

This is part two of a series on nanotechnology and its effect on human health.

In the first article, I provided an overview of the safety concerns associated with manmade nanotechnology, and identified nano-aluminum as a serious threat to our health. The lack of safety studies on most forms of nanotechnology makes it hard to assess and rank the long-term risks posed by the thousands of nanosized ingredients that are being used in food, cosmetics, consumer products, and industry/military applications. However, evidence is pointing to nano-aluminum as being an extremely dangerous nanotechnology.

The sickest people have the highest levels of nano-aluminum and parasites in their bodies, and when they are helped to detox their aluminum and control their parasites, they begin to heal from chronic illness. The presence of nano-aluminum goes hand-in-hand with the presence of parasites. Lets start examining this relationship by looking at nano-aluminum.

The presence of nano-aluminum in our bodies cannot be measured through conventional lab tests. It requires sophisticated electron microscopic examination of samples, which strangely is not available in the United States. A doctor cant just order a nano-aluminum test to check your status, because U.S. labs arent able or arent permitted to do this test.

Please use this link to read the first article in this series:

Nano-Toxicity: Are Nanoparticles in Food and Our Environment the New Health Epidemic?

The Source of Our Nano-Aluminum Exposure

As explained in the...

06:40

Propolis, caffeic acid phenethyl ester, and pollen have beneficial effects on renal injury in hypertensive rats. GreenMedInfo

PMID:  Cell Biochem Funct. 2017 Aug ;35(6):304-314. Epub 2017 Aug 22. PMID: 28833317 Abstract Title:  Effects of propolis, caffeic acid phenethyl ester, and pollen on renal injury in hypertensive rat: An experimental and theoretical approach. Abstract:  The objective of this study was to evaluate the antioxidant effects of propolis, caffeic acid phenethyl ester (CAPE; active compound in propolis), and pollen on biochemical oxidative stress biomarkers in rat kidney tissue inhibited by N() -nitro-L-arginine methyl ester (L-NAME). The biomarkers evaluated were paraoxonase (PON1), oxidative stress index (OSI), total antioxidant status (TAS), total oxidant status (TOS), asymmetric dimethylarginine (ADMA), and nuclear factor kappa B (NF-B). TAS levels and PON1 activity were significantly decreased in kidney tissue samples in the L-NAME-treated group (P 

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06:21

Aquaculture sector loses $1 billion a year to outbreaks of tiny crustaceans infesting and devouring fish farmed for human consumption Health Nut News

Right now, wholesale prices of salmon are 50 percent higher than they were last year, due in part to a surge in parasitic sea lice. And this infestation is threatening to disrupt cultures that count salmon farming as a way of life. The tiny lice are actually little crustaceans that attach themselves to salmon and feed on

06:15

Caffeic acid phenethyl ester reduces ischemia-induced kidney mitochondrial injury in rats. GreenMedInfo

PMID:  Oxid Med Cell Longev. 2017 ;2017:1697018. Epub 2017 Aug 13. PMID: 28883899 Abstract Title:  Caffeic Acid Phenethyl Ester Reduces Ischemia-Induced Kidney Mitochondrial Injury in Rats. Abstract:  During partial nephrectomy, the avoidance of ischemic renal damage is extremely important as duration of renal artery clamping (i.e., ischemia) influences postoperative kidney function. Mitochondria (main producer of ATP in the cell) are very sensitive to ischemia and undergo damage during oxidative stress. Finding of a compound which diminishes ischemic injury to kidney is of great importance. Caffeic acid phenethyl ester (CAPE), biologically active compound of propolis, might be one of the promising therapeutic agents against ischemia-caused damage. Despite wide range of biological activities of CAPE, detailed biochemical mechanisms of its action at the level of mitochondria during ischemia are poorly described and need to be investigated. We investigated if CAPE (22mg/kg and 34mg/kg, injected intraperitoneally) has protective effects against short (20min) and longer time (40min) rat kidney ischemia in an in vitro ischemia model. CAPE ameliorates in part ischemia-induced renal mitochondrial injury, improves oxidative phosphorylation with complex I-dependent substrate glutamate/malate, increases Ca(2+) uptake by mitochondria, blocks ischemia-induced caspase-3 activation, and protects kidney cells from ischemia-induced necrosis. The protective effects on mitochondrial respiration rates were seen after shorter (20min) time of ischemia whereasreduction of apotosis and necrosis and increase in Ca(2+) uptake were revealed after both, shorter and longer time of ischemia.

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05:43

Caffeic acid might be a promising alternative to ameliorate a wide spectrum of disorders due to its complex mechanisms of action. GreenMedInfo

PMID:  Biofactors. 2017 Jul 28. Epub 2017 Jul 28. PMID: 28753257 Abstract Title:  Caffeic acid attenuates the inflammatory stress induced by glycated LDL in human endothelial cells by mechanisms involving inhibition of AGE-receptor, oxidative, and endoplasmic reticulum stress. Abstract:  Type 2 diabetes mellitus is a worldwide epidemic and its atherosclerotic complications determine the high morbidity and mortality of diabetic patients. Caffeic acid (CAF), a phenolic acid present in normal diets, is known for its antioxidant properties. The aim of this study was to investigate CAF's anti-inflammatory properties and its mechanism of action, using cultured human endothelial cells (HEC) incubated with glycated low-density lipoproteins (gLDL). Levels of the receptor for advanced glycation end-products (RAGE), inflammatory stress markers (C reactive protein, CRP; vascular cell adhesion molecule-1, VCAM-1; monocyte chemoattractant protein-1, MCP-1), and oxidative stress and endoplasmic reticulum stress (ERS) markers were evaluated in gLDL-exposed HEC, in the presence/absence of CAF. RAGE silencing or blocking, specific inhibitors for oxidative stress (apocynin, N-acetyl-cysteine), and ERS (salubrinal) were used. The results showed that: (i) gLDL induced CRP synthesis and secretion through mechanisms involving NADPH oxidase-dependent oxidative stress and ERS in HEC; (ii) gLDL-RAGE interaction, oxidative stress, and ERS stimulated the secretion of VCAM-1 and MCP-1 in HEC; and (iii) CAF reduced the secretion of CRP, VCAM-1, and MCP-1 in gLDL-exposed HEC by inhibiting RAGE expression, oxidative stress, and ERS. In conclusion, CAF might be a promising alternative to ameliorate a wide spectrum of disorders due to its complex mechanisms of action resulting in anti-inflammatory and antioxidative properties. 2017 BioFactors, 2017.

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05:42

Marjoram Essential Oil Benefits Sleep, Blood Pressure, Bladder, Gut Natural Blaze

By 

Marjoram essential oil has long been used as a traditional medicine. According to Greek mythology, Aphrodite, goddess of love, once used it as a love potion. Today, the sweet marjoram oil uses and potential healing properties are shared worldwide in commercial products like soaps, shampoos, and creams. Marjoram oil is extracted from the leaves of the perennial plant, Origanum majorana, and is used to treat various ailments orally, topically, and via inhalation.

What is marjoram essential oil used for health-wise? Its primary use is for calming nerves. It also may be used for promoting good blood circulation, lowering blood pressure, alleviating pain, reducing inflammation, and settling digestive problems.

The chemical composition of marjoram essential oil includes the powerful terpinolene, a-terpinene, y-terpinene, terpinen-4-o1, linalyl acetate, p-cymene, sabinene, cis-sabinene hydrate, and linalool.

Nutritionally, two tablespoons of marjoram oil offer the following recommended daily allowances (RDA):

  • Vitamin A 6%
  • Calcium 8%
  • Vitamin C 3.5%
  • Iron 18%                                                                                                

Healing Properties of Marjoram Essential Oil

1. Pain Relief

As an analgesic, marjoram essential oil works to al...

05:33

Apocynin has a protective role in a rat model of traumatic brain injury. GreenMedInfo

PMID:  Neurochem Res. 2017 Aug 7. Epub 2017 Aug 7. PMID: 28786047 Abstract Title:  Protective Role of Apocynin via Suppression of Neuronal Autophagy and TLR4/NF-B Signaling Pathway in a Rat Model of Traumatic Brain Injury. Abstract:  Neuronal autophagy and inflammatory responses are important in the pathogenesis of traumatic brain injury (TBI), and toll-like receptor 4 (TLR4) may play an important role in the related molecular cascade. The present study investigated the protective effect of apocynin, an inhibitor of NADPH oxidase, in a TBI rat model and further examined neuronal autophagy and the TLR4-mediated pathway. Adult male Sprague-Dawley rats were subjected to controlled cortical impact injury and intraperitoneally injected with apocynin (50 mg/kg) immediately after the trauma. In addition to motor and behavioral studies, brain water content and histology analyses were performed. Expression of autophagy-related proteins as well as TLR4/NF-B signaling and inflammatory mediators was analyzed. The apocynin treatment significantly attenuated TBI-induced motor and behavioral impairment, brain edema and neuronal damage in rats. Immunohistochemical and Western blot analyses revealed that apocynin treatment significantly reduced the expression of NOX2, LC3 and Beclin1 in the hippocampus at 12-48 h after injury. Double immunolabelingdemonstrated that apocynin decreased the co-localization of LC3 or TLR4-positive cells with hippocampal neurons at 24 h following TBI. In addition, CD11b (microglial marker) and GFAP (astrocyte marker)-immunopositive cells were also clearly decreased in hippocampal tissues. Meanwhile, protein levels of TLR4, NF-B p65, TNF- and IL-1 were found to be significantly downregulated by Western blot analysis. In conclusion, our findings indicate that the protective effects of apocynin may be related to modulation of neuronal autophagy and the TLR4/NF-B signaling pathway.

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05:05

New Study: Magnesium Found to Treat Depression Better Than Antidepressant Drugs REALfarmacy.com

Source: New Study: Magnesium Found to Treat Depression Better Than Antidepressant Drugs For more content like this visit REALfarmacy.com.

A breakthrough nutritional study conducted at the Larner College of Medicine at the University of Vermont and published in PLoS ONE has found that ...

Source: New Study: Magnesium Found to Treat Depression Better Than Antidepressant Drugs Learn more at REALfarmacy.com - Healthy News and Information.

04:32

Aluminum causes autism? Anti-vaccine Shaw and Tomljenovic again Skeptical Raptor

The Skeptical Raptor, stalking pseudoscience in the internet jungle.

Every morning I wake up with the vain hope that the vaccine deniers will give up on the thoroughly debunked vaccines-cause-autism tropes. And every morning Im disappointed. Todays trope is that vaccine aluminum causes autism. Despite the claims, there still is no evidence. Two of our favorite anti-vaccine shills, Christopher Shaw and Lucija Tomljenovic, have

Skeptical Raptor

04:22

At Least 248 Dead Following 7.1 Magnitude Earthquake in Mexico REALfarmacy.com

Source: At Least 248 Dead Following 7.1 Magnitude Earthquake in Mexico For more content like this visit REALfarmacy.com.

Terribly heart-wrenching news is coming out of Mexico where at least 20 schoolchildren and hundreds of others were killed during collapses and explosions following ...

Source: At Least 248 Dead Following 7.1 Magnitude Earthquake in Mexico Learn more at REALfarmacy.com - Healthy News and Information.

03:47

Report: New Evidence of Ongoing Corruption and Scientific Misconduct at CDC Natural Blaze

misconduct CDC

Kennedy hopes new evidence and a fresh look at criminal misconduct will result in law enforcement action, rigorous and transparent vaccine safety science, and safer vaccines.

Washington, DC In a new report released today, Robert F. Kennedy, Jr. and his team outlined various criminal acts on the part of employees and consultants for the Centers for Disease Control and Prevention (CDC) whose questionable ethics and scientific fraud have resulted in untrustworthy vaccine safety science.

Among other information, Kennedy has found additional evidence of criminal activity by the CDC consultant, Poul Thorsen, the author and principal coordinator of multiple CDC studies exonerating the mercury-based preservative thimerosal in the development of autism.

The new evidence, recently uncovered by the World Mercury Project, shows that Thorsen and his collaborators did not obtain permission from an Institutional Review Board (IRB) to conduct their research, which was published in the New England Journal of Medicine in 2002 and Pediatrics in 2003.

 SEE: CDC Suggest Miscar...

03:46

Treating vitamin D deficiency in children with type I diabetes could improve their glycaemic control GreenMedInfo

PMID:  BMC Res Notes. 2017 Sep 7 ;10(1):465. Epub 2017 Sep 7. PMID: 28882195 Abstract Title:  Treating vitamin D deficiency in children with type I diabetes could improve their glycaemic control. Abstract:  BACKGROUND AND AIMS: The relationship between vitamin D deficiency and type I DM is an ongoing area of interest. The study aims to identify the prevalence of vitamin D deficiency in children and adolescents with T1DM and to assess the impact of treatment of vitamin D deficiency on their glycaemic control.METHODS: Retrospective data was collected from 271 children and adolescents with T1DM. The vitamin D deficient (25(OH)D

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03:46

New Worry for Your Tap Water The Alliance for Natural Health

From The Guardian:

Microplastic contamination has been found in tap water in countries around the world, leading to calls from scientists for urgent research on the implications for health.

Scores of tap water samples from more than a dozen nations were analysed by scientists for an investigation by Orb Media, who shared the findings with the Guardian. Overall, 83% of the samples were contaminated with plastic fibres.

The US had the highest contamination rate, at 94%, with plastic fibres found in tap water sampled at sites including Congress buildings, the US Environmental Protection Agencys headquarters, and Trump Tower in New York. Lebanon and India had the next highest rates.

Comment: Pile this onto the total toxic burden that were subjected to every day. These plastics can also absorb toxic chemicals, which then make their way into virtually everything we eat and drink. As the plastic fibers are so small, water filters do not catch all of them. (Recall our story on the FTC blocking development of a biodegradable plastic that, ironically, could help solve this problem.)

Action Alert! Tell the EPA to follow the law and clean up our drinking water. Please send your message immediately.

03:38

Surprise! Buried Deep in GOP Health Bill The Alliance for Natural Health

The Obamacare repeal is only temporaryexpires in six years.

A few weeks ago, we told you about a new proposal described by nearly everyone as an attempt  to repeal and replace Obamacare. The bill has now been introduced by Sens. Bill Cassidy (R-LA) and Lindsay Graham (R-SC).

Overall, the initiative would eliminate federal subsidies for private insurance and the Medicaid expansion, transforming these funds into block grants to states to spend as they see fit, with some restrictions. States that have Obamacare can keep it if they want, although state governments would need to kick in some of their own money to continue. States that want a different system could make the necessary adjustments.

Some other brief points about the bill:

  • It repeals the individual and employer mandate;
  • It repeals some Obamacare taxes, principally the tax on medical equipment;
  • Like previous repeal/replace proposals, it lifts many restrictions on Health Savings Accounts (HSAs);
  • Obamacare requirements such as essential health benefits are NOT repealed, though states can apply for waivers from those regulations from 2020 through 2026, which means that a future administration could eliminate the waivers and bring back Obamacare rules for everyone;
  • The bill allows all individuals the option to purchase catastrophic health coverage, though these plans would be incorporated into the individual single risk pool, which we have warned against, because it will likely make the catastrophic only policies unaffordable.

Because the Graham-Cassidy legislation will have to move through the budget reconciliation process, Congress deadline to pass it is September 30. After that, it could be brought up down the road, but not soon.

Whether one supports or opposes Obamacare, it is not helpful to advertise a repeal bill that does not actually repeal it at all.

 

03:25

Supplementation with creatine may improve muscle strength parameters in individuals with spinal cord injury. GreenMedInfo

PMID:  J Spinal Cord Med. 2017 Sep 13:1-8. Epub 2017 Sep 13. PMID: 28901216 Abstract Title:  Creatine or vitamin D supplementation in individuals with a spinal cord injury undergoing resistance training: A double-blinded, randomized pilot trial. Abstract:  Purpose Determine whether creatine or vitamin D supplementation improves muscle strength in individuals with spinal cord injury undergoing resistance training. Methods Thirteen male and one female with spinal cord injury, from two Portuguese rehabilitation centers, were randomized to creatine (3g daily), vitamin D (25000 IU each two weeks) or placebo group in a double-blind design. All participants performed progressive resistance training during eight weeks. The outcome measures, obtained at baseline and after intervention, included: Sum of four skinfolds; Corrected arm muscle area; Seated medicine ball throw; Handgrip strength with dynamometer; Manual wheelchair slalom test and one repetition maximum for Chest press, Triceps, Pec deck and Lat pulldown. Vitamin D levels were obtained in all participants before and after intervention. Results 71.4% of participants had deficit values of vitamin D. The corrected arm muscle area improved significantly (p

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03:13

USDA: Fake Organics: Does The Agency Care? The Alliance for Natural Health

We must pressure the federal government to police unscrupulous global players. Action Alert!

Weve been telling you about the influx of fake organic grain imported from overseas. Its especially infuriating that the USDA seems to recognize this problem but is doing very little about it. A 2016 USDA report highlights one such challenge:

As organic production and consumption in Turkey grow, so too do the concerns about fraudulent organic products and lack of inspections. According to a EUROPOL report, some Turkish companies have been involved in relabeling or repackaging products as organic and bringing the counterfeit products into the European Union, even though the products do not meet the organic standards.

One Turkish organic certifier, ETKO, seems to be egregiously at fault. Canada and the European Union have singled out ETKO  for its fraudulent certifications and decertified the firm meaning that ETKO-certified organic products are no longer accepted as organic.

The USDA had problems with ETKO as far back as 2009 but, instead of decertifying this company, actually reached a settlement agreement with them in 2016. The firm is now under audit by USDA. We asked the status of the audit and were told that the agency is still gathering data and will be done soon.

As the saying goes, Fool me once, shame on you. Fool me twice, shame on me. ETKO appears to have  been fooling people for years, based on Canadian and European action, and its time for the USDA to do its job and decertify this company. Not only do consumers unwittingly purchase products falsely labeled by the government as organic, but organic farmers in the US are also affected as they have to compete with fraudulent goods.

Action Alert! Write to Congress, with a copy to the USDA, urging lawmakers to step in to protect consumers and domestic farmers by investigating and if indicated decertifying ETKO. Please send your message immediately.

03:09

Big Brother USDA Wants to Educate You to Support Big Agriculture The Alliance for Natural Health

Thats one takeaway from a report just issued about how to implement the sham GMO labeling law that Congress passed last year. Action Alert!

Recall that GMO labeling advocates were handed a defeat with the passage of the National Bioengineered Food Disclosure Standard. It is a labeling law by only the slimmest definition: food companies must disclose GMO ingredients, but the consumer disclosure can take the form of a scannable QR or other electronic code on the foods packaging.

The law stipulated that the USDA study the challenges of using such codes. What the study (conducted by giant government contractor Deloitte) found is of little surprise.

Significant deficiencies were identified in a GMO labeling system that relies heavily on QR codes to tell consumers about the contents of food. When consumers were observed trying to access the GMO disclosure, researchers observed key technological challenges that prevented nearly all participants from obtaining the information through electronic or digital disclosure methods. As we argued before the law passed, this was always just a ploy to enable Big Food to keep consumers from easily accessing the information they want about the food they buy.

The report provided to USDA also slights Americans understanding of GMOs. Quoting directly: Though many consumers care about the issue of bioengineered food, there is limited understanding of the issueThis limited familiarity may result in soft opinions that are more likely to change over time and be sensitive to question wording. With implementation of the Law, consumer attitudes may shift as information about bioengineered food becomes more readily available.

Translation: many Americans dont buy the propaganda, repeated throughout the report, that bioengineered foods are neither more nor less safe than non-bioengineered alternativesan assertion that is not borne out by the facts.

But dont worry. The study recommends that a consumer education campaign be conducted to straighten us out about GMOs and QR codes. Somewhere, George Orwell is chuckling to himself.

Action Alert! Write to your elected officials and tell them that the new USDA report demonstrates that we need a GMO labeling bill that actually works. Please send your message immediately.

...

03:05

Californians Want Cellular Antennas Right Outside Your Bedroom Window? BolenReport

The California Legislature Thinks Thats OK By Camilla Rees Center for ElectroSmog Prevention (CEP) The California Alliance for Safer Technology (www.CA4ST.org), a consortium of health and environmental advocates, physicians, non-profit leaders, attorneys and government officials is presently appealing to Governor Brown to VETO SB.649. The group is asking all Californians to join in NOW Continue reading Californians Want Cellular Antennas Right Outside Your Bedroom Window?

The post Californians Want Cellular Antennas Right Outside Your Bedroom Window? appeared first on BolenReport.

02:34

Journal republishes withdrawn paper on emergency care prices, amid controversy Retraction Watch

The Annals of Emergency Medicine has republished a controversial paper it withdrew earlier this year which compared the cost of emergency care at different types of facilities. Because the paper drew heavy criticism when it was originally released, the journal has published a revised version, along with several editorials and discussions between the authors and []

The post Journal republishes withdrawn paper on emergency care prices, amid controversy appeared first on Retraction Watch.

02:33

Earthquake Safety: What You Need To Know Doom and Bloom (TM)

EARTHQUAKE SAFETY A 7.1 magnitude earthquake struck Mexico City on Tuesday, September 19, collapsing buildings, killing at least 250, and injuring hundreds more throughout the region.  The latest tremor event came hard on the heels of an 8.1 magnitude quake off the coast just 2 weeks ago, which killed almost 100 and even generated a small tsunami wave. Various aftershocks measuring up to 4.9 have been recorded since Tuesdays quake hit at 1 pm local time. Although there is no

[... Continue Reading]

00:01

Pregnant women exposed to flouride are more likely to have kids with low IQ, study shows Fluoride Action Network

  • The major study is the first of its kind; it involved researchers from Canada, US and Mexico
  • The researchers analyzed data on 300 mother-child pairs from Mexico 
  • They found every 0.5 milligram-per-liter increase of flouride in a pregnant womans urine marked a drop in intelligence scores for their children later in life
  • Experts warn the study, published today, shows flouride is particularly dangerous for brain development during gestation

Pre-natal exposure to fluoride is linked to lower measures of intelligence in children, an unprecedented study has found.

Researchers tracked data on nearly 300 mothers and their children in Mexico, testing the kids cognitive development twice in 12 years.

They found children were not affected by drinking flouride themselves, but tended to have low IQ scores on tests if their mothers flouride in their urine before childbirth.

Every 0.5 milligram-per-liter increase of flouride in a pregnant womans urine marked a drop in intelligence scores for their children later in life.

Experts warn the study, published today, shows flouride is particularly dangerous for brain development during gestation.

The research, the first of its kind, involved researchers from the worlds leading medical centers, including Harvard, McGill University, the University of Michigan, and the National Institute of Public Health of Mexico.

Our study shows that the growing fetal nervous system may be adversely affected by higher levels of fluoride exposure, said Dr. Howard Hu, the studys principal investigator and professor of environmental health, epidemiology and global health at the Dalla Lana School of Public Health.

It also suggests that the prenatal nervous system may be more sensitive to fluoride compared to that of school-aged children.

Flouride first took off as a bone-protected chemical 60 years ago.

Over the years, it has been added to tap water and dental products as well as table salt and milk in the US and Canada, tipped as a health boost.

However, a growing swell of research has emerged in the last few years showing water flouridation may have some cripplingly dangerous side effects, particularly for childrens brains.

While flouride is not added to the tap water in Mexico, many are exposed to the chemical n...

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Wednesday, 20 September

23:54

Fluoride Exposure In Utero Linked To Lower IQ In Kids, Study Says Fluoride Action Network

Year after year, more and more people are becoming aware of the harmful effects fluoride can have on the human body. Fluoride has been a known neurotoxin for a long time, but the government claims it benefits our teeth.

In reality, its not even known to actually prevent the buildup of harmful oral bacteria; however, it is known to be toxic, with long-term ingestion linked to brain, heart, and bone issues. Fluoride is also an endocrine disruptor, and can affect your thyroid gland, pineal gland, and blood sugar levels.

Many universities and established scientific publications have gathered data on the health risks associated with fluoride. For example, a 2014 study conducted by Harvard School of Public Health and Icahn School of Medicine studied the effects of certain developmental neurotoxicants, including fluoride.

The researchers stated that children exposed to fluoride in drinking water showed an average IQ decrement of about seven points in children exposed to raised fluoride concentrations.

Well, another groundbreaking study was just published on Tuesday in the journal Environmental Health Perspectives, further supporting that fluoride exposure can cause a reduction in IQ levels. However, this study was conducted in Mexico, where there is no fluoride added to drinking water (though there is some naturally occurring), meaning that much of the fluoride children are exposed to comes from sources outside of water.

Can you imagine how much fluoride were exposed to, given that its added to most of the drinking water all over North America and its in our conventional toothpaste brands, too?

The study involved approximately 300 sets of mothers and their children in Mexico. The researchers evaluated children on their cognitive development twice over a period of 12 years. To be clear, fluoride isnt actually added to the public water system in Mexico, but children are still exposed to fluoride through toothpaste, naturally-occurring fluoride, supplements, and fluoridated salt, among other sources.

The researchers measured fluoride through urine analysis. The results showed a decrease in intelligence test scores for every 0.5 milligram-per-liter rise in fluoride exposure beyond 0.8 milligrams per liter found in urine. The researchers noted that fluoride exposure in utero was especially influential on IQ.

The study results read:

In this study, higher levels of maternal urinary fluoride during pregnancy (a proxy for prenatal fluoride exposure) that are in the range of levels of exposure in other general population samples of pregnant women as well as nonpregnant adults were associated with lower scores on tests of cognitive function in the offspring at 4 and 612 y old.

The average woman actually had 0.9 milligrams per liter of fluoride in their urine, meaning that many children were affected. Yet these levels are rel...

21:53

Body of missing advocate found Health Nut News

Twyla Roscovich, the 38-year-old filmmaker, activist, and mother vanished on September 7th prompting a widespread search. She was known for creating films about the area she loved in an effort to protect the salmon and the environment and raise awareness about everything from First Nations to oil tankers. Last Friday her family released a written statement saying her body had

21:38

Serum Ferritin and GGT two potent health indicators you need to know Health Nut News

By Dr. Mercola While many health screens and lab tests are overrated or unnecessary, there are a few that are vitally important, such as vitamin D. I recommend checking your vitamin D level at least twice a year. Two other really important tests are serum ferritin (which measures stored iron) and gamma-glutamyl transpeptidase or sometimes called

21:26

How 3 drops of oregano oil and baking soda could heal your lungs Health Nut News

Pneumonia is the 6th leading cause of death worldwide, and oregano oil and baking soda could act as another line of defense! Currently, we use prescription medication to manage respiratory problems. And since the majority of these illnesses are bacterial infections, we use antibiotics to treat them. But Oregano Oil, with its potent antibacterial properties,

21:22

3 things that happen when you stop showering for a month Health Nut News

Im gonna be TMI honest with you guys- I dont ever skip showers. I cant imagine working out and not washing off that sweat. I mean come on, I live in Florida. Im not sure if thats just how Im wired or if Ive just gotten used to it. However, I do know people who dont

20:39

Is PetMed selling opiates for people, not pets? Health Nut News

By Dr. Mercola Every day, 91 Americans die from an opioid overdose, including those obtained via a prescription. Intended to be reserved for only the most serious cases of pain, opioids are being vastly overprescribed, including for noncancer chronic pain, such as back pain or that from osteoarthritis. With overdose deaths on the rise, public health agencies

06:55

Prediabetic? How to Reverse it Naturally GreenMedInfo

Are you one of the 84.1 million people in the United States who has been pre-diagnosed with diabetes? If so, here are practical steps you can take today to turn this looming crisis into a lifetime of better health.

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Saturday, 16 September

04:54

Hixson Utility District admits putting fertilizer, aluminum factory discharge into tap Fluoride Action Network

In this graphic, Hixson Utility District makes a worrisome admission about an intentional contaminant it is being asked to remove fluoride. (Image Hixsonutility.com)

In this graphic, Hixson Utility District makes a worrisome admission about an intentional contaminant it puts into drinking water one it is being asked to remove. Fluoride is approved by the federal government. (Images Hixsonutility.com)

Hixson Utility District faces renewed questions about its use of a contaminant, hydrofluorosilicic acid, which it puts deliberately as policy into the water supply of more than many thousands customers in North Chattanooga.

The public utility, whose board meets Friday at 4 p.m., in its recent Waterworks newsletter says that the acid, called fluoride for short, is a contaminant it identifies as discharge from fertilizer and aluminum factories.

Fluoride is a government-approved industrial waste that proponents say is no danger to public health, one that hardens enamel in the teeth of small children, but one that clean-water advocates insist is connected to nerve system damage and health problems.

The three-member board came under pressure in 2016 to end fluoridation, which brings equipment damage and capital damage with which manager Greg Butler must regularly contend. David Collette, manager of a neighbouring Northwest Utility District in the northern part of Hamilton County, cited equipment damage in calling for an end to fluoridation in summer 2016.

Mr. Collettes board agreed with him and in July ended injection of the chemical. The tide of objections shifted southward. Led by a young musician, activists demanded Hixson end fluoridation. But board members Rebecca Hunter, Jeff Davis and Kenneth Ridge refused to vote on the matter, saying not enough evidence had been presented to warrant reconsideration of fluoride.

Weve researched what we could find out about fluoride, board member Mr. Rich said at the meeting in which the board refused to vote on fluoride, and we found out that if its injected within limits, its been very beneficial in most water companies. When in a r...

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